Evidence map›Paper›PMID 41209846›Full record

ArticleJournal of bone and joint infection2025

A prospective evaluation of the inoculation of homogenised tissue and bone biopsies in blood culture bottles for the diagnosis of orthopaedic-device-related infections.

Ann-Sophie Jacob, Jolien Onsea, Laura Bessems, Pauline Spoormans, Georges Vles, Willem-Jan Metsemakers, Sien Ombelet, Melissa Depypere

Abstract read
In one paragraph

Article in Journal of bone and joint infection, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ann-Sophie JacobDepartment of Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0001-5233-4529
Jolien OnseaDepartment of Trauma Surgery, University Hospitals Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0002-5096-5789
Laura BessemsDepartment of Trauma Surgery, University Hospitals Leuven, Leuven, Belgium.
Pauline SpoormansDepartment of Orthopaedics, University Hospitals Leuven, Leuven, Belgium.
Georges VlesDepartment of Orthopaedics, University Hospitals Leuven, Leuven, Belgium.
Willem-Jan MetsemakersDepartment of Trauma Surgery, University Hospitals Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0002-4114-9093
Sien OmbeletDepartment of Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium.
Melissa DepypereDepartment of Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fracture-related infections (FRIs) and periprosthetic joint infections (PJIs) occur in nearly 2 % of patients with orthopaedic devices, contributing to significant morbidity and mortality. Effective microbiological diagnosis of these infections remains challenging, with the homogenisation of bone/tissue biopsies recognised as the most reliable pre-analytical procedure. This prospective study compared the inoculation of homogenised samples into a BacT/ALERT

Identifiers

PMID41209846
PMCPMC12590579

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.