Evidence map›Paper›PMID 41209740›Full record

ArticleFrontiers in microbiology2025

Molecular epidemiology of

Chanjuan Huangfu, Xiujun Ma, Junjie Fan, Kuo Han, Ti Liu, Zengqiang Kou, Yan Li

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Genomic phylogenetic characterization ofBiosafety and health · 2026
    Article
  2. Article
  3. Identification and phylogenetic analysis of sevenFrontiers in cellular and infection microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chanjuan Huangfu *School of Public Health and Health Management, Shandong First Medical University, Jinan, China.
Xiujun Ma *Shandong Centre for Disease Control and Prevention, Jinan, China.
Junjie FanWeifang Centre for Disease Control and Prevention, Weifang, China.
Kuo HanShandong Centre for Disease Control and Prevention, Jinan, China.
Ti LiuShandong Centre for Disease Control and Prevention, Jinan, China.
Zengqiang KouShandong Centre for Disease Control and Prevention, Jinan, China.
Yan LiShandong Centre for Disease Control and Prevention, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The recent identification of Methods: We characterized 12 Results: Epidemiological data indicated that infections primarily occurred in middle-aged men with occupational livestock exposure. Molecular typing revealed biovar 3 as the predominant type (91.7%), dominated by MLVA-8 genotype 36 and its corresponding MLVA-11 genotype 72 (66.7%). MLVA-16 distinguished 12 unique genotypes. The phylogeny based on cgSNP classified the strains into clades C1 (11 bv. 3 strains) and C2 (one bv. 1 strain). Within clade C1, nine strains in subclade C1-III exhibited ≤119 SNP differences, eight of which formed a local clonal transmission chain (≤52 SNPs) and shared MLVA-11 genotype 72. Subclade C1-I contained two strains with novel genotypes resulting from variations at the Bruce18 and Bruce43 loci. The sole C2 strain differed by only 3 SNPs from the A19 vaccine strain, suggesting a potential vaccine-related origin. Genetic links were also identified with strains from other Chinese provinces, among them Heilongjiang and Inner Mongolia, as well as from several countries, including Mongolia and Russia. Discussion: These findings revealed a complex epidemiological pattern in Shandong, primarily characterized by local transmission chains with occasional external introductions, provided a scientific basis for targeted brucellosis control strategies.

Indexed as

Brucella abortuscgSNPgenotypingMLVAmolecular epidemiology

Identifiers

PMID41209740
PMCPMC12588999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.