Evidence map›Paper›PMID 41209738›Full record

ArticleFrontiers in microbiology2025

Impact of the COVID-19 pandemic on vancomycin-resistant

Maria Lagadinou, Christos Michailides, Christodoulos Chatzigrigoriadis, Ioannis Erginousakis, Prodromos Avramidis, Marina Amerali, Fotini Tasouli, Anna Chondroleou, Katerina Skintzi, Anastasia Spiliopoulou and 4 more

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Temporal Trends and Mortality of Vancomycin-ResistantPathogens (Basel, Switzerland) · 2026
    Observational
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Maria Lagadinou *Department of Internal Medicine, University of Patras, Patras, Greece.
Christos Michailides *Department of Internal Medicine, University of Patras, Patras, Greece.
Christodoulos ChatzigrigoriadisMedical School of Patras, University of Patras, Patras, Greece.
Ioannis ErginousakisMedical School of Patras, University of Patras, Patras, Greece.
Prodromos AvramidisMedical School of Patras, University of Patras, Patras, Greece.
Marina AmeraliDepartment of Internal Medicine, University of Patras, Patras, Greece.
Fotini TasouliMedical School of Patras, University of Patras, Patras, Greece.
Anna ChondroleouNurse Infection Control, University of Patras, Patras, Greece.
Katerina SkintziNurse Infection Control, University of Patras, Patras, Greece.
Anastasia SpiliopoulouDepartment of Microbiology, University of Patras, Patras, Greece.
Fevronia KolonitsiouDepartment of Microbiology, University of Patras, Patras, Greece.
Leonidia LeonidouDepartment of Internal Medicine, University of Patras, Patras, Greece.
Stelios F AssimakopoulosDepartment of Internal Medicine, University of Patras, Patras, Greece.
Markos MarangosDepartment of Internal Medicine, University of Patras, Patras, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Antimicrobial resistance is a critical and growing global health concern. While drug-resistant Gram-negative bacilli pose a significant threat, multidrug-resistant Gram-positive bacteria-such as methicillin-resistant Aim: This study provides an epidemiological analysis of resistant Gram-positive bacteria, focusing on VRE, at a tertiary university hospital in Western Greece from 2018 to 2023. Results: A total of 276 blood cultures with vancomycin-resistant Conclusion: The number of VRE increased over the study period. Linezolid and tigecycline remained largely effective, but emerging resistance patterns-particularly to daptomycin-underscore the urgent need for strengthened antimicrobial stewardship and the development of novel therapeutic options to address rising resistance among Gram-positive pathogens.

Indexed as

antibioticsantimicrobial resistancebacteremiaEnterococcus spp.gram positive

Identifiers

PMID41209738
PMCPMC12593218

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.