Evidence map›Paper›PMID 41209729›Full record

ArticleFrontiers in microbiology2025

Benzophenone-3 remodels gut microbiota diet-dependently to exacerbate non-alcoholic fatty liver disease in zebrafish.

Junyan Tao, Linxuan Tian, Qinyuan Yang, Yao Jiang, Yubo Liu, Junli Wang, Xiong Chen, Hui Gao

Abstract read
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Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Junyan Tao *The Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, School of Public Health, Guizhou Medical University, Guiyang, Guizhou, China.
Linxuan Tian *The Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, School of Public Health, Guizhou Medical University, Guiyang, Guizhou, China.
Qinyuan YangThe Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, School of Public Health, Guizhou Medical University, Guiyang, Guizhou, China.
Yao JiangThe Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, School of Public Health, Guizhou Medical University, Guiyang, Guizhou, China.
Yubo LiuDepartment of Forensic Medicine, Guizhou Medical University, Guiyang, Guizhou, China.
Junli WangThe Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, School of Public Health, Guizhou Medical University, Guiyang, Guizhou, China.
Xiong ChenThe Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, School of Public Health, Guizhou Medical University, Guiyang, Guizhou, China.
Hui GaoKey Laboratory of Fertility Preservation and Maintenance of Ministry of Education, School of Basic Medicine, Ningxia Medical University, Yinchuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Benzophenone-3 (BP3), a prevalent organic UV filter found in aquatic environments and human tissues, poses potential metabolic risks. This study investigated the combined effects of BP3 (10 μg/L) and a high-fat diet (HFD, 24% crude fat) on non-alcoholic fatty liver disease (NAFLD) development in zebrafish, focusing on gut-liver axis disruption via microbiota. Co-exposure to BP3 and HFD significantly worsened hepatic steatosis, as evidenced by increased triglyceride levels, lipid droplets accumulation, and oxidative damage (elevated hepatic MDA levels and decreased hepatic CAT activity). Additionally, this combined exposure induced gut dysbiosis characterized by a marked decrease in

Indexed as

Benzophenone-3diet-dependent mannergut microbiotaNAFLDzebrafish

Identifiers

PMID41209729
PMCPMC12592189

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.