ArticleAJPM focus2026
Impact of Vaccination-Differentiated Public Health and Social Measures on Vaccine Uptake Among the Vaccine Hesitant.
Article in AJPM focus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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10 authors.
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Abstract
Introduction: Vaccine hesitancy poses a hurdle toward achieving high population-level immunity and reducing disease transmission. One policy response adopted during the COVID-19 vaccination campaign was the implementation of vaccination-differentiated public health and social measures. This paper aims to evaluate the impact of vaccination-differentiated public health and social measures on COVID-19 vaccination rates in Singapore, with a specific focus on vaccine-hesitant persons. Methods: An interrupted time series design with segmented linear regression was utilized to assess the impact of the announcement of each vaccination-differentiated public health and social measure on vaccine uptake rates among the vaccine-naive population. Newey-West standard errors with a 7-day lag were applied to address potential autocorrelation in the data. Covariates adjusted for included day of the week, daily numbers of COVID-19-related cases, deaths, hospitalizations, and patients in the intensive care unit. Results: The study found a significant and positive effect of vaccination-differentiated public health and social measure announcements on the daily vaccine uptake rate among the vaccine-naive population, specifically for dining out and patronizing shopping malls. When stratified by age group, the significant and positive effect of the announcement of mall access vaccination-differentiated public health and social measures persisted across all age groups, and it only persisted for individuals aged 13-17, 25-34, and 35-49 years for the announcement of dining vaccination-differentiated public health and social measures. Conclusions: Overall, the findings support the effectiveness of vaccination-differentiated public health and social measures in increasing vaccine uptake rates among vaccine-hesitant persons. However, the compelling evidence for complementary policies should also be considered.
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