ArticleAlpha psychiatry2025
Effects of Hypertension, Uric Acid Level, and Other Physiological Factors on Blood Lithium Concentration/Dose Ratio Values in Patients With Manic Episodes.
Article in Alpha psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Correlation Analysis of Blood Lithium Metabolism Kinetics and Concentration-to-Dose Ratio in Patients With Hypertension and Manic Episodes.Human psychopharmacology · 2026Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To explore the effects of hypertension, uric acid (UA) level, and other physiological factors on blood lithium concentration/dose ratio (C/D; a measure of lithium pharmacokinetics) values in patients experiencing manic episodes. Methods: A total of 644 patients with manic episodes were treated at the study hospital between January and June 2022. Patients were divided into groups according to their systolic and diastolic blood pressure (BP) as well as blood glucose, triglyceride, and UA levels. The effects of these factors on blood lithium C/D values after lithium carbonate treatment were examined. Results: The mean blood lithium C/D value of all study participants was 0.832 ± 0.248 mmol·L Conclusion: Hypertension and elevated UA levels can affect the blood lithium C/D value in patients with manic episodes. Personalized treatment approaches that take these physiological factors into account may help reduce treatment risks.
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