ArticleAlpha psychiatry2025
Genetic Insights Into Skin Diseases and Depression: Evidence From East Asian Mendelian Randomization Analysis.
Article in Alpha psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Sleep Duration and Epilepsy Risk: Mendelian Randomization and Functional Validation of CACNA1A rs2228130-Related Inhibitory Synaptic Dysfunction.Neuromolecular medicine · 2026Article
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Authors and funding
2 authors.
Funding
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Abstract
Background: This Mendelian randomization (MR) study systematically examines the causal links between skin disorders and depression in individuals of East Asian descent. Methods: MR analysis employed summary-level genome-wide association study (GWAS) data from East Asian populations. Exposures included six skin diseases: atopic dermatitis (AD) ( Results: In East Asian ancestries, a significant causal relationship was identified between urticaria and an increased risk of MDD (odds ratio [OR] = 1.220, 95% CI 1.022-1.457, Conclusions: This study identifies a significant positive causal relationship between urticaria and MDD risk and no significant association between psoriasis and MDD in East Asian populations, contrasting with previous European findings. Results for other skin diseases align with previous studies. These findings highlight the need for ancestry-specific research to inform personalized prevention and intervention strategies.
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