ArticleTransplantation direct2025
Long-term Graft and Patient Survival in Kidney Transplant Recipients With High Levels of Preformed DSAs (MFI > 3000): A Propensity Score-matched Analysis.
Article in Transplantation direct, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Long-term HLA-incompatible kidney transplant outcomes.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Kidney transplant recipients with preformed donor-specific antibodies (DSAs) are at higher risk for antibody-mediated rejection (AMR) and graft failure. This study assesses outcomes during a 15-y period, comparing patients with high levels of preformed DSAs to a matched cohort of recipients without DSA. Methods: This retrospective study includes 95 patients with high levels of preformed DSAs, defined by DSA levels (mean fluorescence intensity > 3000). Using propensity score matching, 88 of these patients were matched to 154 recipients without DSA based on age, sex, transplant year, cold ischemia time, and other clinical factors. Outcomes included occurrence of AMR, T cell-mediated rejection, and long-term allograft and patient survival. Results: The mean follow-up after transplantation was 11.9 ± 5.6 y. Among the matched patients, kidney allograft survival rates after transplantation at 5, 10, and 15 y were 90.5%, 79.5%, and 72.8% for the patients without preformed DSA and 86.7%, 60.2%, and 47.6% for the patients with high levels of preformed DSAs ( Conclusions: Although patients with high levels of preformed DSAs have a higher risk of graft loss, their long-term survival did not differ significantly from recipients without DSA, supporting the use of intensive immunosuppression in this population.
Identifiers
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Registered trials
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