ArticleInternational journal of endocrinology2025
Association Between Novel Lipid and Anthropometric Indices and Sleep Duration and Disturbance: A Cross-Sectional NHANES Study 2005-2020.
Article in International journal of endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Lipid accumulation product and its association between new onset stroke among middle age and elderly population.BMC cardiovascular disorders · 2026Article
- Environmental adaptation and sleep disturbance: a cross-sectional study reveals distinct metabolic risk profiles in long-term high-altitude residents versus the general population.Frontiers in psychiatry · 2026Article
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4 authors.
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Abstract
Objectives: Insufficient or excessive sleep and dyslipidemia are significant cardiovascular risk factors. Whilst the relationship between sleep duration and traditional lipid indices are well described, the connection to novel lipid and anthropometric indices remains unclear. This study examines these associations using National Health and Nutrition Examination Survey (NHANES) data from 2005 to 2020. Methods: This cross-sectional study analyzed data from 9847 adults from NHANES 2005-2020, excluding those with major cardiovascular disease and cancer. Sleep duration was categorized as insufficient (< 7 h), normal (7-8 h), and excessive (> 8 h). Self-reported sleep disturbance was documented. Novel indices included non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR), Triglyceride to HDL-Cholesterol (TG/HDL), Triglyceride-Glucose (TyG) Index, Visceral Adiposity Index (VAI), Lipid Accumulation Product (LAP), Conicity Index (CI), Body-Roundness Index (BRI), A Body Shape Index (ABSI), and Weight-adjusted waist index (WWI). Generalized additive models (GAMs) with spline smoothing and threshold analysis assessed nonlinear associations, adjusting for confounders. Weighted multivariate linear regression evaluated linear associations. Results: Insufficient sleep was associated with higher TyG combined with waist-to-height ratio (TyG-WHtR) ( Conclusions: Insufficient, excessive sleep duration and sleep disturbance are associated with adverse lipid and anthropometric profiles, indicating increased cardiometabolic risk. Optimal sleep duration and addressing sleep disturbance could mitigate these risks. Further research is needed to understand the underlying mechanisms.
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