ArticleMethodsX2025
Acupuncture combined with exercise therapy for Sarcopenia in the elderly: A multicenter randomized controlled study protocol.
Article in MethodsX, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- From "spleen governing muscle" to gut microbiota: mechanisms of sarcopenic obesity in perimenopausal women.Frontiers in microbiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sarcopenia (SP) is an age-related disorder characterized by progressive loss of muscle strength, mass, and limb dysfunction, severely compromising the quality of life and life safety in older adults. With the global aging population, the incidence of this disease has been escalating, posing a significant public health challenge. Preclinical studies have demonstrated that acupuncture effectively mitigates muscle loss in rats; however, the field currently lacks robust randomized controlled trials (RCTs), marked by limitations such as the absence of sham acupuncture controls, multicenter designs, and standardized outcome metrics. Therefore, this study integrates acupuncture with exercise therapy, incorporating the following design highlights: A multicenter approach to enhance research reliability; A control group receiving sham acupuncture combined with exercise to eliminate the placebo effect; The most comprehensive and validated set of outcome measures to ensure study rigor and expand the conceptual framework for sarcopenia assessment. This research aims to provide robust evidence for acupuncture as an effective adjuvant therapy for SP. The study has been registered with the International Traditional Medicine Clinical Trials Registry Platform (ITMCTR2024000374).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.