Evidence map›Paper›PMID 41209231›Full record

ArticleQuantitative imaging in medicine and surgery2025

Fully automated deep learning model for the evaluation of cavum septum pellucidum development in normal fetuses using magnetic resonance imaging: a Chinese cohort study.

Zhengyang Zhu, Junxia Wang, Qing Hu, Ye Han, Jiaojiao Wu, Xin Zhang, Ming Li, Xu Yang, Zhuoru Jiang, Yuying Liu and 8 more

Abstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Zhengyang Zhu *Department of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.ORCID https://orcid.org/0000-0001-9916-3480
Junxia Wang *Department of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Qing Hu *Department of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Ye HanDepartment of Research and Development, United Imaging Intelligence, Shanghai, China.
Jiaojiao WuDepartment of Research and Development, United Imaging Intelligence, Shanghai, China.
Xin ZhangDepartment of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Ming LiDepartment of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Xu YangDepartment of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Zhuoru JiangDepartment of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Yuying LiuDepartment of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Xuefeng MaMedical Imaging Center, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Shenyu FanDepartment of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Haocheng WangDepartment of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Yukun ZhangMedical Imaging Center, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Tang TangDepartment of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Feng ShiDepartment of Research and Development, United Imaging Intelligence, Shanghai, China.
Chenchen YanDepartment of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Bing ZhangDepartment of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The cavum septum pellucidum (CSP) is an essential landmark in evaluating fetal brain development. The aim of this study was to assess the development of normal fetal CSP across different gestational ages (GAs) in a Chinese cohort using a deep learning (DL) model, and to provide reference for magnetic resonance imaging (MRI) prenatal diagnosis. Methods: A retrospective analysis of 1,047 normal pregnant participants (mean GA 31.21±3.81 weeks) in the second and third trimester was conducted. Fetuses with central nervous system (CNS) anomalies were excluded. A fully automated DL model was developed to measure CSP volume, CSP length, CSP width, CSP height, ratio of CSP volume to whole brain volume, and ratio of CSP volume to cerebrum volume. Linear regression and second-order polynomial regression was used to assess the relationship between CSP measurements and GA. Results: CSP volume showed a second-order polynomial correlation with GA ( Conclusions: CSP volume, width, and height reach a maximum between 28 and 32 weeks of gestation. CSP length exhibits an upward trend after 22 weeks. The ratio of CSP volume to whole brain volume and ratio of CSP volume to cerebrum volume illustrate a downward trend after 22 weeks.

Indexed as

cavum septum pellucidum (CSP)Deep learning (DL)fetal developmentfetal magnetic resonance imaging (fetal MRI)

Identifiers

PMID41209231
PMCPMC12591797

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.