Evidence map›Paper›PMID 41209140›Full record

ArticleReviews in cardiovascular medicine2025

Potential of Epicardial Adipose Tissue Quantification in Predicting Atrial Thrombus in Patients With Atrial Fibrillation.

Huan Wang, Tianze Wang, Manyun Tang, Peizhu Dang, Changying Zhao, Yang Yan, Jianying Li, Tao Shi, Jianxin Guo

Abstract read
In one paragraph

Article in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Huan WangDepartment of Radiology, The First Affiliated Hospital of Xi'an Jiaotong University, 710061 Xi'an, Shaanxi, China.ORCID https://orcid.org/0000-0001-5059-2962
Tianze WangDepartment of Neurosurgery, The First Affiliated Hospital of Xi'an Jiaotong University, 710061 Xi'an, Shaanxi, China.ORCID https://orcid.org/0009-0008-9840-0833
Manyun TangDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, 710061 Xi'an, Shaanxi, China.ORCID https://orcid.org/0000-0002-7165-2650
Peizhu DangDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, 710061 Xi'an, Shaanxi, China.ORCID https://orcid.org/0000-0002-7771-3127
Changying ZhaoDepartment of Cardiovascular Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, 710061 Xi'an, Shaanxi, China.ORCID https://orcid.org/0000-0002-2260-314X
Yang YanDepartment of Cardiovascular Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, 710061 Xi'an, Shaanxi, China.ORCID https://orcid.org/0000-0001-7167-0261
Jianying LiGE Healthcare, Computed Tomography Research Center, 100000 Beijing, China.ORCID https://orcid.org/0000-0003-4034-0555
Tao ShiDepartment of Cardiovascular Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, 710061 Xi'an, Shaanxi, China.ORCID https://orcid.org/0009-0002-2503-2845
Jianxin GuoDepartment of Radiology, The First Affiliated Hospital of Xi'an Jiaotong University, 710061 Xi'an, Shaanxi, China.ORCID https://orcid.org/0000-0003-3655-8914

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atrial fibrillation (AF) can increase the risk of stroke by five-fold; strokes associated with AF are more likely to lead to death or severe disability in patients. Thus, preventing the formation of thrombosis is of vital importance in the treatment of patients with AF. Epicardial adipose tissue (EAT) is a risk factor for AF and is closely associated with many AF-related complications. However, to our knowledge, no in-depth studies on the relationship between the incidence of thrombosis in AF patients and EAT have been conducted. Therefore, it is of great clinical significance to explore the potential of EAT quantification in predicting intra-atrial thrombosis in patients with AF. Methods: This is a case-control study; patients with AF who underwent coronary computed tomography angiography (CCTA) were included. These patients were divided into the thrombus group and the non-thrombus group according to the results of transesophageal echocardiography (TEE). The volume of EAT, the mean density of EAT, and the ratio of EAT volume to the whole heart volume were measured by CCTA, and the data of the two groups were compared. Meanwhile, the diagnostic efficiency of using these parameters was analyzed. Result: A total of 308 patients with AF who underwent both TEE and CCTA were enrolled in this study. After a 1:1 propensity score matching (PSM) analysis based on age and sex, a total of 76 patients were finally included. Compared with the patients in the non-thrombus group, those in the thrombus group had a larger volume of EAT (132.38 ± 45.25 cm Conclusions: The EAT volume may be a potential biomarker for predicting intra-atrial thrombosis in patients with AF; however, further validation is required to confirm the diagnostic value.

Indexed as

atrial fibrillationepicardial adipose tissueintra-atrial thrombusprediction

Identifiers

PMID41209140
PMCPMC12593815

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.