Evidence map›Paper›PMID 41209139›Full record

ReviewReviews in cardiovascular medicine2025

Pulse Field Ablation: An Update on Energy-Specific Adverse Events.

Minghao Zhou, Hongliang Yang, Huan Sun, Ming Yu, Daoyuan Si, Yuquan He

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Minghao ZhouDepartment of Cardiology, China-Japan Union Hospital of Jilin University, Jilin Provincial Molecular Biology Research Center for Precision Medicine of Major Cardiovascular Disease, 130033 Changchun, Jilin, China.ORCID https://orcid.org/0009-0006-4483-4455
Hongliang YangDepartment of Cardiology, China-Japan Union Hospital of Jilin University, Jilin Provincial Molecular Biology Research Center for Precision Medicine of Major Cardiovascular Disease, 130033 Changchun, Jilin, China.ORCID https://orcid.org/0000-0002-7654-4667
Huan SunDepartment of Cardiology, China-Japan Union Hospital of Jilin University, Jilin Provincial Molecular Biology Research Center for Precision Medicine of Major Cardiovascular Disease, 130033 Changchun, Jilin, China.ORCID https://orcid.org/0000-0002-8283-8143
Ming YuDepartment of Cardiology, China-Japan Union Hospital of Jilin University, Jilin Provincial Molecular Biology Research Center for Precision Medicine of Major Cardiovascular Disease, 130033 Changchun, Jilin, China.ORCID https://orcid.org/0000-0003-4264-5811
Daoyuan SiDepartment of Cardiology, China-Japan Union Hospital of Jilin University, Jilin Provincial Molecular Biology Research Center for Precision Medicine of Major Cardiovascular Disease, 130033 Changchun, Jilin, China.ORCID https://orcid.org/0000-0003-3493-2300
Yuquan HeDepartment of Cardiology, China-Japan Union Hospital of Jilin University, Jilin Provincial Molecular Biology Research Center for Precision Medicine of Major Cardiovascular Disease, 130033 Changchun, Jilin, China.ORCID https://orcid.org/0000-0002-3439-260X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulsed field ablation (PFA) represents a paradigm shift in cardiac ablation technology. Indeed, PFA, a non-thermal technique, achieves homogeneous tissue effects by delivering ultrashort, high-frequency electric pulses. Moreover, PFA has emerged as a prominent ablation strategy in electrophysiology laboratories worldwide. While current clinical evidence demonstrated promising outcomes and expanded applications for existing PFA platforms, energy-specific difficulties complicated the definition of safety boundaries, particularly in patients with clinical complications. Furthermore, substantial heterogeneity among commercial PFA systems impeded procedural standardization. Therefore, this review aimed to synthesize contemporary perspectives on mitigating these energy-specific adverse events, with emphasis on modifiable perioperative factors. The evidence of safety across commercially available PFA systems with divergent catheter design philosophies was concurrently evaluated to examine how design strategies influence procedural safety profiles.

Indexed as

atrial fibrillationcoronary artery spasmenergy-specific adverse eventhemolysispulsed field ablationvagal ganglionated plexus

Identifiers

PMID41209139
PMCPMC12593765

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.