ArticleFrontiers in immunology2025
Clinical and diagnostic insights into Brucella spondylitis: a comprehensive retrospective study.
Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Shifting risk profiles in the systemic-to-focal transition of brucellosis: a multicenter analysis of spondyloarthritis development.BMC infectious diseases · 2026Article
- Comparative analysis of pathogen detection methods in spinal infections: a retrospective study of 287 cases.BMC infectious diseases · 2026Article
- Brucellar spondylodiscitis mimicking lumbar discectomy with cauda equina syndrome: A case report.The Journal of international medical research · 2026Article
- Diagnostic Value of Metagenomic Next-Generation Sequencing for Suspected Native Spinal Brucella Infection: A Multicenter Study.Neurospine · 2026Article
- Brucellar spondylitis is associated with disturbance in gut microbiota and histamine metabolism associated inflammation.Frontiers in cellular and infection microbiology · 2026Article
- Metagenomic Next-Generation Sequencing in Brucellar Spondylitis with Discordant Serologic Findings in a Non-Endemic Region: A Case Report and Literature Review.Infection and drug resistance · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study evaluates the diagnostic value of etiological and serological testing and the clinical characteristics of spine brucellosis. Methods: A retrospective analysis was conducted on 200 cases of spine brucellosis diagnosed between 2012 and 2025, alongside 200 non-infected controls. Bacterial cultures, clinical features, serological results (Standard Agglutination Test [SAT] and Rose Bengal Test [RBT]), and imaging findings were analyzed. Results: Among 200 patients with spinal involvement, Conclusions: Brucella Spondylitis, typically chronic and lumbar-predominant, presents with bone destruction, gap stenosis, and disc herniation on imaging. Diagnosis relies on lumbar tissue culture, SAT, RBT, and CT. Early diagnosis and combined medical-surgical management improve outcomes.
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