Evidence map›Paper›PMID 41208919›Full record

ReviewJournal of pharmaceutical analysis2025

Brain organoids-on-chip for neural diseases modeling: History, challenges and trends.

Hongyong Zhang, Nan Huang, Sumin Bian, Mohamad Sawan

Abstract readReview
In one paragraph

Review in Journal of pharmaceutical analysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Using Brain Organoids to Explore Human Neurobiology.Cellular and molecular neurobiology · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Novel advanced patient-derivedFrontiers in neurology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hongyong ZhangZhejiang University, Hangzhou, 310027, China.
Nan HuangZhejiang University, Hangzhou, 310027, China.
Sumin BianCenBRAIN Neurotech, School of Engineering, Westlake University, Hangzhou, 310030, China.
Mohamad SawanCenBRAIN Neurotech, School of Engineering, Westlake University, Hangzhou, 310030, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain organoid-on-chip platforms have emerged as groundbreaking tools in neural disease modeling and drug discovery, offering a unique and highly accurate simulation of human organ physiology and function compared with traditional cell culture systems. This technology is a harmonious fusion of organ-on-a-chip and organoid culture technologies, leveraging their strengths to provide the most realistic

Indexed as

Brain organoidsBrain organoids-on-chipNeural diseases modelOrgan-on-chipPersonalized medicine

Identifiers

PMID41208919
PMCPMC12594919

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.