Evidence map›Paper›PMID 41208811›Full record

ArticleACS applied bio materials2025

Polyphenol-Mediated Antibody Functionalization of Titanium Peroxide Nanoparticles for Cancer Cell Targeting.

Hiroaki Akasaka, Makiko Nakahana, Masao Nakayama, Kenta Morita, Mohammed Salah, Naritoshi Mukumoto, Yasuyuki Shimizu, Ruixain Zhangzhu, Chiaki Ogino, Christina Cortez-Jugo and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied bio materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hiroaki AkasakaDivision of Radiation Oncology, Graduate School of Medicine, Kobe University, 7-5-2 Kusunokicho, Chuo-ku, Kobe 650-0017, Japan.ORCID 0000-0003-1017-5229
Makiko NakahanaDivision of Radiation Oncology, Graduate School of Medicine, Kobe University, 7-5-2 Kusunokicho, Chuo-ku, Kobe 650-0017, Japan.
Masao NakayamaDivision of Radiation Therapy, Kita-Harima Medical Center, 926-250 Ichibacho, Ono, Hyogo 675-1392, Japan.
Kenta MoritaDepartment of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodaicho, Nada-ku, Kobe 657-8501, Japan.ORCID 0000-0002-2156-4812
Mohammed SalahDivision of Radiation Oncology, Graduate School of Medicine, Kobe University, 7-5-2 Kusunokicho, Chuo-ku, Kobe 650-0017, Japan.
Naritoshi MukumotoDivision of Radiation Oncology, Kobe University Hospital, 7-5-2 Kusunokicho, Chuo-ku, Kobe 650-0017, Japan.
Yasuyuki ShimizuDivision of Radiation Oncology, Kobe University Hospital, 7-5-2 Kusunokicho, Chuo-ku, Kobe 650-0017, Japan.
Ruixain ZhangzhuDivision of Radiation Oncology, Graduate School of Medicine, Kobe University, 7-5-2 Kusunokicho, Chuo-ku, Kobe 650-0017, Japan.
Chiaki OginoDepartment of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodaicho, Nada-ku, Kobe 657-8501, Japan.ORCID 0000-0002-8906-7724
Christina Cortez-JugoDepartment of Chemical Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia.ORCID 0000-0001-5341-175X
Joseph J RichardsonSchool of Engineering, RMIT University, Melbourne, Victoria 3001, Australia.
Frank CarusoDepartment of Chemical Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia.ORCID 0000-0002-0197-497X
Ryohei SasakiDivision of Radiation Oncology, Kobe University Hospital, 7-5-2 Kusunokicho, Chuo-ku, Kobe 650-0017, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell targeting would benefit various biotechnological applications such as disease diagnosis and cancer therapy. However, efficiently functionalizing nanoparticles with targeting ligands such as antibodies remains challenging. For example, poly(acrylic acid)-modified titanium peroxide NPs (PAATiO

Indexed as

AntibodiesAntineoplastic AgentsBiocompatible MaterialsNanoparticlesPolyphenolsTitaniumAnimalsCell Line, TumorCell ProliferationCell SurvivalDrug Screening Assays, AntitumorHumansHyaluronan ReceptorsMaterials TestingMiceParticle SizeAntibodiesAntineoplastic AgentsBiocompatible MaterialsHyaluronan ReceptorsPolyphenolsTitaniumdrug delivery systemsmetal−phenolic networksnanoparticlesphenolicsradiation sensitizerradiotherapy

Identifiers

PMID41208811
PMCPMC12709614

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.