Evidence map›Paper›PMID 41208207›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins.

Xiao Duan, Chong Zhang, Stanislav Ott, Zhiyi Zhang, Christiane Ruse, Sven Dannhäuser, Robert Jacobi, Nadine Ehmann, Divya Sachidanandan, Georg Nagel and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xiao DuanDepartment of Neurophysiology, Institute of Physiology, University Wuerzburg, 97070, Wuerzburg, Germany.
Chong ZhangDepartment of Neurophysiology, Institute of Physiology, University Wuerzburg, 97070, Wuerzburg, Germany.
Stanislav OttProgram in Neuroscience and Behavioral Disorders, Duke-NUS Medical School, 169857, Singapore, Singapore.
Zhiyi ZhangProgram in Neuroscience and Behavioral Disorders, Duke-NUS Medical School, 169857, Singapore, Singapore.
Christiane RuseBuchmann Institute of Molecular Life Sciences, Goethe University, 60438, Frankfurt, Germany.
Sven DannhäuserDepartment of Neurophysiology, Institute of Physiology, University Wuerzburg, 97070, Wuerzburg, Germany.
Robert JacobiDepartment of Neurophysiology, Institute of Physiology, University Wuerzburg, 97070, Wuerzburg, Germany.
Nadine EhmannDepartment of Animal Physiology, Institute of Biology, Leipzig University, 04103, Leipzig, Germany.
Divya SachidanandanDepartment of Animal Physiology, Institute of Biology, Leipzig University, 04103, Leipzig, Germany.
Georg NagelDepartment of Neurophysiology, Institute of Physiology, University Wuerzburg, 97070, Wuerzburg, Germany.
Manfred HeckmannDepartment of Neurophysiology, Institute of Physiology, University Wuerzburg, 97070, Wuerzburg, Germany.
Robert J KittelDepartment of Animal Physiology, Institute of Biology, Leipzig University, 04103, Leipzig, Germany.
Alexander GottschalkBuchmann Institute of Molecular Life Sciences, Goethe University, 60438, Frankfurt, Germany.
Adam Claridge-ChangProgram in Neuroscience and Behavioral Disorders, Duke-NUS Medical School, 169857, Singapore, Singapore.
Shiqiang GaoDepartment of Neurophysiology, Institute of Physiology, University Wuerzburg, 97070, Wuerzburg, Germany.ORCID https://orcid.org/0000-0001-6190-9443

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Effective optogenetic inhibition of neuronal activity requires tools that reliably silence neurons across cell types and conditions. K

Indexed as

ChannelrhodopsinsOptogeneticsAnimalsCaenorhabditis elegansDrosophilaNeuronsPotassiumSodiumChannelrhodopsinsPotassiumSodiumdepolarization and hyperpolarizationKalium channelrhodopsin (KCR)neuronal activationneuronal inhibitionoptogenetics

Identifiers

PMID41208207
PMCPMC12866730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.