Evidence map›Paper›PMID 41207929›Full record

ArticleInflammopharmacology2025

Rosa moschata leaf extract modulates complete freund's adjuvant-induced polyarthritis in Wistar rats via regulation of pro-inflammatory and inflammatory biomarkers.

Amr S Abouzied, Uzma Saleem, Maryam Farrukh, Umme Farwa, Areej M Alsolami, Fatima A Jaber, Tourki A S Baokbah, Ibrahim Aljaezi, Nouf Abdullah Alharbi, Muhammad Ajmal Shah and 2 more

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Article in Inflammopharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Amr S AbouziedDepartment of Pharmaceutical Chemistry, College of Pharmacy, University of Hail, Hail, Saudi Arabia.
Uzma SaleemCollege of Pharmacy, University of the Punjab, Lahore, Pakistan. uzma.pharmacy@pu.edu.pk.
Maryam FarrukhDepartment of Pharmacology, Faculty of Pharmaceutical Sciences, Government College University, Faisalabad, 38000, Pakistan.
Umme FarwaDepartment of Pharmacology, Faculty of Pharmaceutical Sciences, Government College University, Faisalabad, 38000, Pakistan.
Areej M AlsolamiDepartment of Biology, College of Science, Jouf University, Sakaka, Saudi Arabia.
Fatima A JaberDepartment of Biological Sciences, College of Science, University of Jeddah, Jeddah, Saudi Arabia.
Tourki A S BaokbahDepartment of Medical Emergency Services, College of Health Sciences, Al Qunfudhah, Umm Al-Qura University, Al Qunfudhah, Saudi Arabia.
Ibrahim AljaeziDepartment of Pharmacology, College of Pharmacy, Najran University, Najran, Saudi Arabia.
Nouf Abdullah AlharbiDepartment of Basic Health Sciences, College of Applied Medical Sciences, Qassim University, Buraydah, Saudi Arabia.
Muhammad Ajmal ShahDepartment of Pharmacy, Hazara University, Mansehra, Pakistan. ajmalshah@hu.edu.pk.
Ana Sanchez SilvaFaculty of Pharmacy, University of Coimbra, Polo III, Azinhaga de Sta Comba, Coimbra, Portugal.
Norah K AlgarzaeDepartment of Physiology, College of Medicine, King Saud University, Riyadh, Saudi Arabia. nalgarzae@ksu.edu.sa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rosa moschata is well known plant for its high levels of nutrients, including quercetin and phenolic compounds, which are believed to reduce inflammation. The purpose of the current study was to assess the anti-polyarthritis potential of R. moschata leaf extract (RMLE) utilizing complete Freund's adjuvant (CFA) in rats. Hydro ethanol extract was prepared by microwave assisted extraction method and its phytochemical characterization was performed by GCMS analysis. Six groups of albino rats (n = 6) were made. Polyarthritis was induced by injecting 0.1 mL of CFA into the back paw of rats. Extract treated groups received RMLE at 150, 300, and 600 mg/kg p.o. for 4 weeks. The body weight, paw diameter, arthritic index was determined at first on 3

Indexed as

Anti-Inflammatory AgentsArthritis, ExperimentalInflammationPlant ExtractsPlant LeavesRosaAnimalsBiomarkersDose-Response Relationship, DrugFreund's AdjuvantMaleOxidative StressRatsRats, WistarAnti-Inflammatory AgentsBiomarkersFreund's AdjuvantPlant ExtractsComplete freund’s adjuvantInflammationOxidative stress markersPolyarthritisRosa moschata

Identifiers

PMID41207929

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.