ArticleClinical oral investigations2025
Long term dental implant survival and bone level changes with special emphasis on radiation therapy after free fibula flap reconstruction - a retrospective study.
Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Dental implant rehabilitation after jaw tumor resection: a mini-review of protocols and quality of life across treatment modalities.Annals of medicine and surgery (2012) · 2026Article
- Failure of salvage therapies in radiation-induced necrosis of a free fibula flap: a case report.Annals of medicine and surgery (2012) · 2026Article
- Accuracy of CAD/CAM planned mandibular reconstruction with scapula free flaps in reconstructive head and neck surgery - A single center study.Oral and maxillofacial surgery · 2026Article
- Conservative Retention of Pre-Existing Dental Implants Contralateral to Adjuvant Radiotherapy for Maxillary Oral Squamous Cell Carcinoma: A 4-Year Follow-Up Case Report.Case reports in dentistry · 2026Article
- Posterior airway space following mandibular reconstruction using microvascular free flaps in oral cancer patients in relation to radiotherapy: a single-center study.Frontiers in oncology · 2026Article
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10 authors.
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Abstract
objectivesThis study aimed to investigate the long-term survival of dental implants in patients after ablative resection of the maxilla or mandible and consecutive reconstruction with microvascular free fibula flaps (FFF). MATERIALS AND
methodsPatients treated with a FFF reconstruction of the mandible/maxilla and dental implant insertion were included. Implant survival and the influence of age, gender, radiotherapy, and localization were evaluated. Moreover, mesial and distal bone resorption was recorded. Implant survival was assessed using Kaplan-Meier methods and Cox regression, while bone loss was analyzed with linear mixed models. Multiple testing was adjusted by Scheffé's method; significance was set at p < 0.05.
resultsIn total, 53 patients with 257 implants were evaluated. The mean observation period was 64 months. The cumulative survival rate was 98.4% at 1 year, 95.7% after 3 years, and 91.8% at 5 years. After five years, adjuvant radiotherapy was associated with reduced implant survival (73.8%) and significantly increased distal bone loss (p = 0.009). Moreover, native bone (mesial: 3.2 ± 0.6; distal 3.2 ± 0.8) demonstrated significantly greater bone loss compared with fibula bone (mesial: 2.6 ± 1.6; distal 2.8 ± 1.7).
conclusionAdjuvant radiotherapy results in a markedly reduced implant survival and a significantly greater marginal bone (distal) loss after five years. CLINICAL RELEVANCE: Dental implants reveal higher survival in fibula bone after mandibular/maxillary reconstruction with microvascular FFF when irradiation was performed prior to reconstruction with a FFF and in patients without irradiation.
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