Evidence map›Paper›PMID 41207911›Full record

SynthesisNeurosurgical review2025

Endovascular and surgical treatment of superior cerebellar artery aneurysms: a systematic review and meta-analysis of outcomes and complications.

Emmanuel O Mensah, Shashvat Purohit, Vitor Lauar Pimenta de Figueiredo, Jay Patel, Omar Alwakaa, Neel Mehta, Megh Prajapati, Rishi Aeleti, Yew-Weng Fong, Christopher S Ogilvy

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Emmanuel O MensahNeurosurgical Division, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Shashvat PurohitNeurosurgical Division, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Vitor Lauar Pimenta de FigueiredoNeurosurgical Division, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Jay PatelNeurosurgical Division, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Omar AlwakaaNeurosurgical Division, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Neel MehtaHarvard Medical School, Boston, MA, USA.
Megh PrajapatiDepartment of Biomedical Engineering, Cornell University, Ithaca, NY, USA.
Rishi AeletiDepartment of Neurobiology and Behavior, Cornell University, Ithaca, NY, USA.
Yew-Weng FongNeurosurgical Division, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Christopher S OgilvyNeurosurgical Division, Beth Israel Deaconess Medical Center, Boston, MA, USA. cogilvy@bidmc.harvard.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesSuperior cerebellar artery (SCA) aneurysms are rare and technically challenging to treat. While both endovascular and microsurgical approaches can be effective, the optimal treatment strategy remains unclear. This systematic review and meta-analysis compare the safety and efficacy of endovascular versus microsurgical treatment of SCA aneurysms.

methodsA systematic search of EMBase, PubMed, and the Web of Science identified studies reporting outcomes of SCA aneurysms treated endovascularly or surgically. Primary outcomes included complication and mortality rates, aneurysm occlusion, and functional outcomes measured by the Glasgow Outcome Scale (GOS) or modified Rankin Scale (mRS). Good functional recovery was defined as GOS > 3 or mRS < 3. Single- and double-arm meta-analyses were performed in R.

resultsThirteen studies comprising 370 patients (89 males, 232 females), with a mean age of 54.1 years were included. 227 patients were treated endovascularly and 143 patients surgically, of which 52.3% of aneurysms were ruptured. Overall, complication, mortality, complete occlusion, and good recovery rates were 14.5%, 4.4%, 85.7%, and 87.2%, respectively. Surgical treatment had higher complications (36.2% vs. 8.1%, p = 0.053) and mortality (7.4% vs. 2.7%, p = 0.060), approaching statistical significance. Surgical treatment yielded significantly higher occlusion rates than endovascular treatment (92.8% vs. 79.8%, p = 0.028), while endovascular therapy was associated with better functional recovery (93.3% vs. 70.9%, p = 0.0196). Mean radiologic and clinical follow-up durations were 28.4 and 27.6 months, respectively.

conclusionBoth endovascular and surgical treatments are viable for SCA aneurysms. Endovascular therapy offers lower complication and mortality rates, while microsurgical treatment achieves higher complete occlusion. Treatment decisions should be tailored to patient and aneurysm characteristics. Further prospective studies, including the role of flow diversion, are needed to optimize treatment selection.

Indexed as

CerebellumEndovascular ProceduresIntracranial AneurysmNeurosurgical ProceduresHumansMicrosurgeryPostoperative ComplicationsTreatment OutcomeEndovascularMeta-analysisMicrosurgeryPosterior circulationSuperior cerebellar artery aneurysm

Identifiers

PMID41207911

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.