Trial reportLasers in medical science2025
Type of study: original study.
Trial report in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose Photobiomodulation(PBM) shows conflicting results in periodontal regeneration due to varied wavelengths and PBM protocols. This study aimed to evaluate the clinical, radiographic, and microbiological outcomes of PBM using different wavelengths, i.e., single (SWPBM) and dual wavelengths(DWPBM) as adjuncts to inorganic bovine bone matrix in management of intrabony periodontal defects (IBD). Methodology: This randomized clinical trial included 30 IBDs, allocated to Control, SWPBM using 810 nm diode laser and DWPBM using 810 and 650 nm diode lasers. Probing pocket depth(PPD), Clinical attachment level(CAL), Gingival recession(GR), Plaque index(PI), Gingival index(GI) were recorded at baseline,3, and 6 months. Defect depth(DD), defect angle(DA), linear bone fill(LBF), bone density(BD), and defect volume(DV) were assessed at baseline and 6 months. Microbial levels of periodontal pathogens were evaluated at baseline and 3 months. Early Healing Score(EHS) and pain were recorded on days 1, 7, and 14.
resultsDWPBM demonstrated greater PPD reduction(Mean reduction(MD)-0.70 mm), CAL gain, and higher EHS on Day 7(p = 0.05). DWPBM showed greater DD reduction(MD = 0.50 mm, p = 0.01), and enhanced LBF (MD = 0.82 mm, p = 0.04). Levels of periodontal pathogens achieved substantial reductions at 3 months in DWPBM compared to Control or SWPBM.
conclusionDWPBM demonstrated superior clinical outcomes, enhanced LBF and reduced periodontal pathogens, suggesting its role as a valuable therapeutic modality. CLINICAL
trial registrationThe study design was reviewed and approved by the Institutional review board and Institutional Ethical Committee provided the ethical clearance (Ref: Project No. IEVDC/23/PG01/PI/IVV/05). The study was registered with clinical trials registry of India (CTRI/2023/07/054740).
Indexed as
Identifiers
41207910What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.