Evidence map›Paper›PMID 41207742›Full record

ReviewPediatric clinics of North America2026

The Pediatric Clinician's Approach to Acute or Chronic Neurologic Symptoms in Children with Sickle Cell Disease.

Djamila L Ghafuri, Lori C Jordan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pediatric clinics of North America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Djamila L GhafuriDivision of Pediatric Neurology, Department of Pediatrics, 2200 Children's Way, DOT 11212, Nashville, TN 37232, USA.
Lori C JordanDivision of Pediatric Neurology, Department of Pediatrics, 2200 Children's Way, DOT 11212, Nashville, TN 37232, USA. Electronic address: lori.jordan@vumc.org.

Funding

Mentoring in Patient-Oriented Research focused on Neurological Complications of Sickle Cell DiseaseK24HL147017 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI JORDAN, LORI CHAFFIN · 2019 to 2023
$547k
NHLBI NIH HHS K24 HL147017
6 · The paper itself

Abstract

Neurologic symptoms are common in children with sickle cell disease (SCD) and may cause significant morbidity and mortality. Organized by neurologic chief complaint, this article reviews current knowledge on pathophysiology, clinical presentation, diagnostic strategies, and first-line treatments for neurologic complications in children with SCD, including headache, first-time seizure, cognitive concerns, gait abnormality, stroke, and transient ischemic attack. Children with SCD with poor school performance should be assessed for silent cerebral infarct. Our goal is to provide primary care pediatric clinicians with the knowledge and tools necessary for optimizing medical care for children with SCD experiencing acute and chronic neurologic morbidity.

Indexed as

Anemia, Sickle CellNervous System DiseasesAcute DiseaseChildChronic DiseaseHumansAbnormal gaitAphasiaHeadachesHemiparesisSeizuresSickle cell diseaseVision loss

Identifiers

PMID41207742
PMCPMC13452262

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.