ArticleNucleic acids research2026
The 3D Genome Browser 2.0: an enhanced online platform for visualizing and analyzing 3D genome architecture.
Article in Nucleic acids research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Article
- Interplay between genomic architecture alterations and GDF6 regulation: A candidate mechanism in Nablus mask-like facial syndrome.HGG advances · 2026Article
- scRiskDB: a single-cell epigenomic resource linking complex traits to regulatory mechanisms across human tissues.Database : the journal of biological databases and curation · 2026Article
- Distinguishing benign from pathogenic duplications involving GPR101 and VGLL1-adjacent enhancers in the clinical setting with the bioinformatic tool POSTRE.NPJ genomic medicine · 2026Article
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Authors and funding
7 authors.
Funding
Abstract
The 3D Genome Browser 2.0 (https://3dgenome.fsm.northwestern.edu) is a significantly enhanced online platform designed for the exploration and analysis of 3D genome architecture data, with easy integration with other omics data such as ChIP-seq and ATAC-seq. This major update introduces a completely redesigned user interface (UI) and the addition of many novel analytical features, empowering researchers to effectively explore the extensive collection of the hosted 3D genome datasets and analyze their own data on a local computer. The browser includes an expanded and manually curated data repository, which now incorporates over 700 bulk and single-cell 3D genome datasets, with key annotations such as compartment, topologically associating domains, and loops. We also added a novel structural variation analysis module, which allows users to visualize and reconstruct chromatin contacts maps in the context of genomic rearrangements and facilitate the detection of enhancer-hijacking events. We rebuilt the platform's architecture from the ground up, resulting in substantial performance gains. The modern and intuitive UI ensures that these powerful analytical tools are accessible and easy to navigate, facilitating a streamlined and efficient workflow for users from diverse research backgrounds. The 3D Genome Browser 2.0 serves as a central, open-access resource poised to accelerate discoveries in the field of genomics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.