Evidence map›Paper›PMID 41206936›Full record

ArticleBioinformatics (Oxford, England)2025

HoloFoodR: a statistical programming framework for holo-omics data integration workflows.

Tuomas Borman, Artur Sannikov, Robert D Finn, Morten Tønsberg Limborg, Alexander B Rogers, Varsha Kale, Kati Hanhineva, Leo Lahti

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tuomas BormanDepartment of Computing, University of Turku, Turku 20014, Finland.ORCID 0000-0002-8563-8884
Artur SannikovDepartment of Life Technologies, University of Turku, Turku 20014, Finland.ORCID 0000-0001-7765-123X
Robert D FinnWellcome Genome Campus, EMBL-EBI, Hinxton, Cambridgeshire CB10 1SA, United Kingdom.ORCID 0000-0001-8626-2148
Morten Tønsberg LimborgCenter for Evolutionary Hologenomics, GLOBE Institute, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 1353, Denmark.ORCID 0000-0002-7718-6531
Alexander B RogersWellcome Genome Campus, EMBL-EBI, Hinxton, Cambridgeshire CB10 1SA, United Kingdom.ORCID 0000-0002-4283-6135
Varsha KaleWellcome Genome Campus, EMBL-EBI, Hinxton, Cambridgeshire CB10 1SA, United Kingdom.ORCID 0000-0002-3503-6383
Kati HanhinevaDepartment of Life Technologies, University of Turku, Turku 20014, Finland.ORCID 0000-0001-6834-7375
Leo LahtiDepartment of Computing, University of Turku, Turku 20014, Finland.ORCID 0000-0001-5537-637X

Funding

Danish National Research Foundation DNRF143Horizon2020 Project FindingPhenoJane and Aatos Erkko Foundation and the Research Council of Finland 321716Jane and Aatos Erkko Foundation and the Research Council of Finland 334814Research Council of Finland 330887
6 · The paper itself

Abstract

summaryHolo-omics is an emerging research area that integrates multi-omic datasets from the host organism and its microbiome to study their interactions. Recently, curated and openly accessible holo-omic databases have been developed. The HoloFood database, for instance, provides nearly 10 000 holo-omic profiles for salmon and chicken under controlled treatments. However, bridging the gap between holo-omic data resources and algorithmic frameworks remains a challenge. Combining the latest advances in statistical programming with curated holo-omic data sets can facilitate the design of open and reproducible research workflows in the emerging field of holo-omics. AVAILABILITY AND IMPLEMENTATION: HoloFoodR R/Bioconductor package and the source code are available under the open-source Artistic License 2.0 at the package homepage https://doi.org/10.18129/B9.bioc.HoloFoodR.

Indexed as

Computational BiologyGenomicsSoftwareAlgorithmsAnimalsChickensMicrobiotaSalmonWorkflow

Identifiers

PMID41206936
PMCPMC12617744

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.