Evidence map›Paper›PMID 41206836›Full record

ArticleInsights into imaging2025

Age-dependent prevalence of the Notch of Harty (pseudolesion of the tibial plafond) in children, adolescents, and young adults.

Pauline Maria Hiller, Maximilian Schmalfuss, Lara Diedrichsen, Tobias Johannes Dietrich, Simon Wildermuth, Stephan Waelti, Anna Falkowski, Nicole Graf, Tim Steffen Fischer

Abstract read
In one paragraph

Article in Insights into imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pauline Maria HillerDivision of Radiology and Nuclear Medicine, HOCH Health, Cantonal Hospital St. Gallen, St. Gallen, Switzerland. pauline.hiller@uzh.ch.ORCID http://orcid.org/0009-0006-5964-2210
Maximilian SchmalfussDivision of Radiology and Nuclear Medicine, HOCH Health, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
Lara DiedrichsenDivision of Radiology and Nuclear Medicine, HOCH Health, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
Tobias Johannes DietrichDivision of Radiology and Nuclear Medicine, HOCH Health, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
Simon WildermuthDivision of Radiology and Nuclear Medicine, HOCH Health, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
Stephan WaeltiDivision of Radiology and Nuclear Medicine, HOCH Health, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
Anna FalkowskiDivision of Radiology and Nuclear Medicine, Cantonal Hospital Winterthur, Winterthur, Switzerland.
Nicole GrafClinical Trials Unit, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
Tim Steffen FischerDivision of Radiology and Nuclear Medicine, HOCH Health, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe notch of Harty (NOH) is a pseudolesion located at the distal tibial plafond that can mimic a clinically significant osteochondral lesion. Reported prevalence in an adult population ranged between 25% and 45%, but the prevalence in younger age groups is unknown. In this study, we assessed the age-dependent prevalence of the NOH in a young population to investigate potential remodeling over time. MATERIALS AND

methodsA retrospective analysis of a single-center database included 895 ankle MRIs of patients aged 6-25 years between 2018 and 2022. Cases with significant artifacts or pathological conditions were excluded. The NOH was categorized into types 1 (fluid-filled) and 2 (cartilage-filled), and measurements were taken for mediolateral, craniocaudal, and anteroposterior dimensions. Logistic and linear regression models with restricted cubic splines assessed age-related trends. Radiographic sensitivity for NOH detection was evaluated in 252 radiographs with MRI-confirmed NOH as a secondary endpoint.

resultsThe overall prevalence of NOH in this study population was 47.1% (14.9% type 1 and 31.6% type 2). Type 1 prevalence peaked at age 8 and declined into adulthood, while type 2 prevalence peaked at age 14 and stabilized through adolescence. The NOH size increased with age until 16 years and subsequently decreased. Radiographic sensitivity for detecting NOH was 51.2%.

conclusionThe NOH is more common in younger individuals, with prevalence and size decreasing with age. This supports its classification as a developmental variant characterized by age-related remodeling. CRITICAL RELEVANCE STATEMENT: This study provides novel insights into the age-dependent prevalence and remodeling of the NOH, enhancing diagnostic precision and improving differentiation between developmental variants and pathological findings in clinical radiology. KEY POINTS: The study investigates the age-dependent prevalence of the NOH. Results show developmental remodeling patterns with prevalence peaking in younger individuals. Data support the theory of NOH being a developmental variant.

Indexed as

Ankle jointDevelopmental variantMagnetic resonance imagingPseudolesion

Identifiers

PMID41206836
PMCPMC12597854

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.