ArticleEuropean journal of pediatrics2025
Feasibility and early outcomes of intact cord resuscitation without special equipment in extremely preterm infants born at 23-25 weeks of gestation: A case series.
Article in European journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Deferred cord clamping (DCC) enhances placental transfusion, yet its feasibility in extremely preterm infants requiring resuscitation remains uncertain. Intact cord resuscitation (ICR) may allow simultaneous placental transfusion and stabilization. This study evaluated the feasibility and short-term outcomes of ICR in infants born at 23
conclusionIn this case-series, ICR was feasible without specialized equipment in extremely preterm infants and was not associated with adverse outcomes. The procedure appeared to support early hemodynamic stabilization and short-term survival, providing preliminary observations that warrant confirmation in larger prospective studies. WHAT IS KNOWN: • ICR was shown to be feasible and safe in extremely preterm infants born at 23-25 weeks of gestation, even without specialized resuscitation trolleys. • Compared with early cord clamping, ICR was associated with higher Apgar scores, improved hemodynamic stability, higher hemoglobin levels, and enhanced early survival. WHAT IS NEW: • Deferred cord clamping (DCC) increases blood volume, hemoglobin, reduces transfusion needs, and lowers intraventricular hemorrhage (IVH) risk in neonates. • Intact cord resuscitation (ICR) has been proposed to combine placental transfusion with timely stabilization, though its feasibility in this high-risk group is still debated.
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