Evidence map›Paper›PMID 41206833›Full record

ArticleEuropean journal of pediatrics2025

Feasibility and early outcomes of intact cord resuscitation without special equipment in extremely preterm infants born at 23-25 weeks of gestation: A case series.

Dogan Kaymaz, Ferhan Demirtas, Deniz Uzun, Yasemin Ezgi Kostekci, Emel Okulu, Omer Erdeve, Fatma Begum Atasay, Saadet Arsan

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Article in European journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Dogan KaymazDivision of Neonatology, Department of Pediatrics, Ankara University Faculty of Medicine, Mamak, Ankara, 06500, Türkiye. dogankaymaz5@gmail.com.
Ferhan DemirtasDivision of Neonatology, Department of Pediatrics, Ankara University Faculty of Medicine, Mamak, Ankara, 06500, Türkiye.
Deniz UzunDepartment of Pediatrics, Ankara University Faculty of Medicine, Ankara, Türkiye.
Yasemin Ezgi KostekciDivision of Neonatology, Department of Pediatrics, Ankara University Faculty of Medicine, Mamak, Ankara, 06500, Türkiye.
Emel OkuluDivision of Neonatology, Department of Pediatrics, Ankara University Faculty of Medicine, Mamak, Ankara, 06500, Türkiye.
Omer ErdeveDivision of Neonatology, Department of Pediatrics, Ankara University Faculty of Medicine, Mamak, Ankara, 06500, Türkiye.
Fatma Begum AtasayDivision of Neonatology, Department of Pediatrics, Ankara University Faculty of Medicine, Mamak, Ankara, 06500, Türkiye.
Saadet ArsanDivision of Neonatology, Department of Pediatrics, Ankara University Faculty of Medicine, Mamak, Ankara, 06500, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deferred cord clamping (DCC) enhances placental transfusion, yet its feasibility in extremely preterm infants requiring resuscitation remains uncertain. Intact cord resuscitation (ICR) may allow simultaneous placental transfusion and stabilization. This study evaluated the feasibility and short-term outcomes of ICR in infants born at 23

conclusionIn this case-series, ICR was feasible without specialized equipment in extremely preterm infants and was not associated with adverse outcomes. The procedure appeared to support early hemodynamic stabilization and short-term survival, providing preliminary observations that warrant confirmation in larger prospective studies. WHAT IS KNOWN: • ICR was shown to be feasible and safe in extremely preterm infants born at 23-25 weeks of gestation, even without specialized resuscitation trolleys. • Compared with early cord clamping, ICR was associated with higher Apgar scores, improved hemodynamic stability, higher hemoglobin levels, and enhanced early survival. WHAT IS NEW: • Deferred cord clamping (DCC) increases blood volume, hemoglobin, reduces transfusion needs, and lowers intraventricular hemorrhage (IVH) risk in neonates. • Intact cord resuscitation (ICR) has been proposed to combine placental transfusion with timely stabilization, though its feasibility in this high-risk group is still debated.

Indexed as

Infant, Extremely PrematureResuscitationUmbilical Cord ClampingApgar ScoreFeasibility StudiesFemaleGestational AgeHumansInfant, NewbornMalePregnancyRetrospective StudiesTreatment OutcomeCord clampingEarly survivalExtremely prematureIntact cord resuscitation

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.