Evidence map›Paper›PMID 41206473›Full record

ArticleNucleic acids research2026

The ProteomeXchange consortium in 2026: making proteomics data FAIR.

Eric W Deutsch, Nuno Bandeira, Yasset Perez-Riverol, Vagisha Sharma, Jeremy J Carver, Luis Mendoza, Deepti J Kundu, Chakradhar Bandla, Selvakumar Kamatchinathan, Suresh Hewapathirana and 10 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

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  10. Identification of a conserved gene family with an essential role inProceedings of the National Academy of Sciences of the United States of America · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Eric W DeutschInstitute for Systems Biology, Seattle WA 98109, United States.ORCID 0000-0001-8732-0928
Nuno BandeiraCenter for Computational Mass Spectrometry, University of California, San Diego (UCSD), La Jolla, CA 92093, United States.
Yasset Perez-RiverolEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, United Kingdom.ORCID 0000-0001-6579-6941
Vagisha SharmaDepartment of Genome Sciences, University of Washington, Seattle WA 98195, United States.
Jeremy J CarverCenter for Computational Mass Spectrometry, University of California, San Diego (UCSD), La Jolla, CA 92093, United States.
Luis MendozaInstitute for Systems Biology, Seattle WA 98109, United States.
Deepti J KunduEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, United Kingdom.
Chakradhar BandlaEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, United Kingdom.
Selvakumar KamatchinathanEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, United Kingdom.
Suresh HewapathiranaEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, United Kingdom.
Zhi SunInstitute for Systems Biology, Seattle WA 98109, United States.
Shin KawanoSchool of Frontier Engineering, Kitasato University, Kanagawa 252-0373, Japan.
Shujiro OkudaNiigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan.ORCID 0000-0002-7704-8104
Brian ConnollyDepartment of Genome Sciences, University of Washington, Seattle WA 98195, United States.
Brendan MacLeanDepartment of Genome Sciences, University of Washington, Seattle WA 98195, United States.
Michael J MacCossDepartment of Genome Sciences, University of Washington, Seattle WA 98195, United States.
Tao ChenBeijing Proteome Research Center, National Center for Protein Sciences, Beijing Institute of Lifeomics, Beijing 102206, China.
Yunping ZhuBeijing Proteome Research Center, National Center for Protein Sciences, Beijing Institute of Lifeomics, Beijing 102206, China.ORCID 0000-0002-7320-7411
Yasushi IshihamaGraduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan.ORCID 0000-0001-7714-203X
Juan Antonio VizcaínoEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, United Kingdom.ORCID 0000-0002-3905-4335

Funding

Seattle Quant: A Resource for the Skyline Software EcosystemR24GM141156 · NIGMS · UNIVERSITY OF WASHINGTON · PI Michael MacCoss · 2021 to 2026
$6.7M
Shortening the development cycle time of Trans Proteomic Pipeline tools with high performance computingR01GM087221 · NIGMS · INSTITUTE FOR SYSTEMS BIOLOGY · PI DEUTSCH, ERIC, MORITZ, ROBERT L · 2010 to 2021
$6.0M
Collaborative Microbial Metabolite CenterU24DK133658 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PIETER C DORRESTEIN · 2022 to 2026
$2.9M
Global proteomics mass spectrometry data sharing infrastructureR24GM148372 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Nuno Bandeira · 2023 to 2026
$2.8M
Advancing data and metadata standards for proteomics mass spectraR24GM127667 · NIGMS · INSTITUTE FOR SYSTEMS BIOLOGY · PI DEUTSCH, ERIC · 2017 to 2019
$1.2M
Biotechnology and Biological Sciences Research Council BB/S01781X/1Biotechnology and Biological Sciences Research Council BB/T019670/1Biotechnology and Biological Sciences Research Council BB/V018779/1Biotechnology and Biological Sciences Research Council BB/X001911/1Biotechnology and Biological Sciences Research Council BB/Y513829/1Chinese National Infrastructure for Protein ScienceELIXIREngineering and Physical Sciences Research Council EP/Y035984/1Fonds National de la Recherche Luxembourg C19/BM/13684739Japan Science and Technology Agency 15650519Japan Science and Technology Agency 18063028Japan Science and Technology Agency JPMJND2304National Key Research and Development Program of China 2021YFA1301603National Key Research and Development Program of China 2024YFE0202700NIDDK NIH HHS U24 DK133658NIGMS NIH HHS R01 GM087221NIGMS NIH HHS R24 GM127667NIGMS NIH HHS R24 GM141156NIGMS NIH HHS R24 GM148372NIH HHS R01 GM087221NIH HHS R24 GM127667NIH HHS R24 GM141156NIH HHS R24GM148372NIH HHS U24DK133658Open Targets OTAR3091Panorama Partners ProgramUniversity of Washington UWPR95794Wellcome TrustWellcome Trust 223745/Z/21/Z
6 · The paper itself

Abstract

The ProteomeXchange consortium of proteomics resources (http://www.proteomexchange.org) was established to standardize open data practices in the mass spectrometry (MS)-based proteomics field. Here, we describe the main developments in ProteomeXchange in the last 3 years. The six member databases of ProteomeXchange, spread out in three different continents, are the PRIDE database, PeptideAtlas, MassIVE, jPOST, iProX, and Panorama Public. We provide updated data submission statistics, showcasing that the number of datasets submitted to ProteomeXchange resources has continued to accelerate every year. Through June 2025, 64 330 datasets had been submitted to ProteomeXchange resources, and from those, 30 097 (47%) just in the last 3 years. We also report on the improvements in the support for the standards developed by the Proteomics Standards Initiative, e.g. for Universal Spectrum Identifiers and for SDRF (Sample and Data Relationship Format)-Proteomics. Additionally, we highlight the increase in data reuse activities of public datasets, including targeted reanalyses of datasets of different proteomics data types, and the development of novel machine learning approaches. Finally, we summarize our plans for the near future, covering the development of resources for controlled-access human proteomics data, and for the support of non-MS proteomics approaches.

Indexed as

Databases, ProteinProteomeProteomicsHumansMachine LearningMass SpectrometrySoftwareProteome

Identifiers

PMID41206473
PMCPMC12807779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.