ArticleWorld journal of microbiology & biotechnology2025
Single-Cell oils from oleaginous yeasts: a scalable biotechnological source of novel larvicides against Aedes aegypti.
Article in World journal of microbiology & biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Aedes aegypti shows increasing resistance to chemical larvicides, underscoring the need for scalable biological alternatives. Single-cell oils (SCOs) from oleaginous yeasts, enriched in unsaturated fatty acids, were evaluated as larvicides. Yeasts from soils and decaying fruits were screened for lipid accumulation under nitrogen limitation, identified by molecular methods, optimized in shake flasks across pH, carbon source, and carbon-to-nitrogen (C/N) ratios, and the top strain was scaled in a 7-L bioreactor. SCOs were extracted and characterized by FTIR, GC-MS, and NMR. Larvicidal activity against third-instar A. aegypti was assessed by mortality, pupation delay, and inhibition of adult emergence, and IC
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