Trial reportSleep & breathing = Schlaf & Atmung2025
Effectiveness of strenghtning oropharyngeal myofunctional therapy combined with cervical spine exercises in mild to moderate obstructive sleep apnoea.
Trial report in Sleep & breathing = Schlaf & Atmung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Controlled Prospective Evidence of Rapid Maxillary Expansion Efficacy in Pediatric Obstructive Sleep Apnea: A Systematic Review Update.Journal of clinical medicine · 2026Review
- Rehabilitation and therapeutic exercise in obstructive sleep apnea: a perspective beyond the apnea-hypopnea index.Frontiers in medicine · 2026Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the effectiveness of an intervention programme combining Oropharyngeal Myofunctional Therapy (OMT) and cervical spine exercises in the general population with mild to moderate Obstructive Sleep Apnoea (OSA), analysing its impact on respiratory variables (AHI, MSatO MATERIALS AND
methodsA single-blind randomised clinical trial with 32 participants diagnosed with mild to moderate OSA, assigned into two groups: control (n = 16) and intervention (n = 16). Both groups received hygiene- and diet-related recommendations, and the intervention group completed an OMT programme and cervical spine exercises over 20 weeks (May 2023-November 2024). The respiratory variables were evaluated using respiratory polygraphy, and daytime sleepiness and quality of life were measured using the Epworth Sleepiness Scale and EuroQol-5D scales, respectively.
resultsNo statistically significant differences were found between groups (Median [IQR]): Apnoea-hypopnoea index (2.0 [-6/6], CI 95%, p = 0.86), Mean oxygen saturation (-0.5 [-1/0], CI 95%, p = 0.43), Oxygen Desaturation index (1.0 [-1/5], CI 95%, p = 0.72), Time with oxygen saturation below 90% (1.0 [0/3], CI 95%, p = 0.10), Epworth Sleepiness Scale score (-1.5 [-4/0], CI 95%, p = 0.83), and EuroQol-5D quality of life questionnaire (5.0 [0-10], CI 95% p = 0.08).
conclusionThe comprehensive 20-week OMT programme and cervical spine exercises showed no effectiveness in improving respiratory parameters, daytime sleepiness or quality of life in patients with mild to moderate OSA compared to hygiene- and diet-related measures alone. The null results observed in this study suggest relevant clinical implications, such as the limited efficacy of low-frequency OMT protocols.
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Registered trials
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