Observational studySleep & breathing = Schlaf & Atmung2025
Can speckle tracking echocardiography unmask cardiac involvement in obesity hypoventilation syndrome?
Observational study in Sleep & breathing = Schlaf & Atmung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionObesity hypoventilation syndrome (OHS) is characterized by morbid obesity; most patients have class 3 obesity with a body mass index (BMI) > 35 kg/m², which is linked to breathing disorders during sleep and hypoventilation during the day, manifested as hypercapnic symptoms. Speckle tracking echocardiography (STE) provides segmental or global measurement of myocardial deformation, or "strain," in all heart chambers. It has the benefit of circumventing many of the conventional echocardiographic limitations. Our study aimed to develop an echocardiographic screening method for OHS and to assess its severity by using two-dimensional (2D) speckle tracking echocardiography (STE) for the early identification of subclinical LV impairment.
methodsAn observational cross-sectional study was conducted between July 2023 and August 2024 at the Cardiology and Chest Departments of Zagazig University Hospitals, in collaboration with the Cardiology Department at Al-Ahrar Teaching Hospital. Demographic and clinical characteristics, BMI, neck circumference, sleep assessment scores, polysomnography, and speckle tracking echocardiography were done.
resultsFifty-eight patients were classified according to STE findings into two groups: [Group I] 39 cases (67.2%) with impaired global longitudinal strain (GLS) and [Group II] 19 cases (32.8%) with normal GLS. GLS was meaningfully more impaired in severe illness compared to mild illness. In Group I, GLS showed a negative correlation with BMI.
conclusionsSubclinical LV systolic impairment was present in 67.2% of OHS cases. LVGLS was more impaired in the severe stage (severe AHI). A higher AHI was associated with impaired LVGLS.
Indexed as
Identifiers
41205063What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.