Evidence map›Paper›PMID 41205017›Full record

ReviewCurrent HIV/AIDS reports2025

Envisioning a Multidisciplinary HBV Cure Research Agenda.

Karine Dubé, Ali Ahmed, Chari Cohen, Yasmin Ibrahim, George A Yendewa, Edward R Cachay, Su Wang, Kristen Marks, Arthur Y Kim, Jeremy Sugarman and 3 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current HIV/AIDS reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Karine DubéDivision of Infectious Diseases and Global Public Health, University of California San Diego School of Medicine, 9500 Gilman Drive, 0507, La Jolla, CA, USA. kdube@health.ucsd.edu.
Ali AhmedDivision of Infectious Diseases and Global Public Health, University of California San Diego School of Medicine, 9500 Gilman Drive, 0507, La Jolla, CA, USA.
Chari CohenHepatitis B Foundation, Doylestown, PA, USA.
Yasmin IbrahimHepatitis B Foundation, Doylestown, PA, USA.
George A YendewaCase Western Reserve University School of Medicine, Cleveland, OH, USA.
Edward R CachayDivision of Infectious Diseases and Global Public Health, University of California San Diego School of Medicine, 9500 Gilman Drive, 0507, La Jolla, CA, USA.
Su WangCooperman Banabas Medical Center, RWJ Barnabas-Rutgers Medical Group, Livingston, NJ, USA.
Kristen MarksWeill Cornell Medicine, New York, NY, USA.
Arthur Y KimHarvard Medical School, Boston, MA, USA.
Jeremy SugarmanJohns Hopkins Berman Institute for Bioethics, Baltimore, MD, USA.
David L ThomasJohns Hopkins University School of Medicine, Baltimore, MD, USA.
Chloe L ThioJohns Hopkins University School of Medicine, Baltimore, MD, USA.
Debika BhattacharyaDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.

Funding

The Long-Acting/Extended Release Antiretroviral Resource Program (LEAP)R24AI118397 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Charles W. Flexner · 2015 to 2026
$9.4M
Human Genetic determinants of HBV recoveryR01AI148049 · NIAID · JOHNS HOPKINS UNIVERSITY · PI DUGGAL, PRIYA, THOMAS, DAVID L · 2020 to 2025
$4.7M
NIAID NIH HHS R01 AI148049NIAID NIH HHS R24 AI118397NIH HHS R24 AI118397
6 · The paper itself

Abstract

purpose of reviewWe examine the current understanding of the multidisciplinary aspects of hepatitis B cure research, such as socio-behavioral sciences, ethics, community engagement, and translational and implementation science. RECENT

findingsThe peer-reviewed literature on the multi-disciplinary aspects of HBV cure research is gradually expanding, although several areas still require attention. These deficiencies include: the acceptability of HBV treatment discontinuations, HBV-related stigma, the impact of co-infections (e.g., HIV), and the translation of discoveries to resource-limited settings. This review highlights the importance of a multidisciplinary framework that bridges socio-behavioral sciences, ethics, community engagement, and translational and implementation science to help ensure the development of an effective, acceptable, scalable and equitable HBV cure.

Indexed as

Biomedical ResearchHepatitis BHepatitis B virusInterdisciplinary ResearchHumansCommunity engagementEthicsHBV cure researchHBV-HIV co-infectionReviewSocio-behavioral sciences

Identifiers

PMID41205017
PMCPMC12596300

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.