Evidence map›Paper›PMID 41204976›Full record

ArticleBrain structure & function2025

Left area PF as a neural marker of technical reasoning.

Giovanni Federico, Ciro Rosario Ilardi, Paola Marangolo, Chloé Bryche, Maximilien Metaireau, Alexandre Bluet, Mathieu Lesourd, Yves Rossetti, François Osiurak

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Article in Brain structure & function, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Giovanni FedericoDepartment of Education, Psychology and Communication, Suor Orsola Benincasa University, Corso Vittorio Emanuele, 292, Naples, 80135, Italy. research@giovannifederico.net.
Ciro Rosario IlardiDepartment of Education, Psychology and Communication, Suor Orsola Benincasa University, Corso Vittorio Emanuele, 292, Naples, 80135, Italy.
Paola MarangoloDepartment of Humanities, Federico II University, Naples, Italy.
Chloé BrycheLaboratoire d'Étude des Mécanismes Cognitifs (EA 3082), Université de Lyon, Lyon, France.
Maximilien MetaireauUniversité Marie et Louis Pasteur, INSERM, UMR 1322 LINC, Besançon, 25000, France.
Alexandre BluetKarolinska Institutet, Stockholm, Sweden.
Mathieu LesourdUniversité Marie et Louis Pasteur, INSERM, UMR 1322 LINC, Besançon, 25000, France.
Yves RossettiMouvement, Handicap, et Neuro-Immersion, Hospices Civils de Lyon et Centre de Recherche en Neurosciences de Lyon, Hôpital Henry Gabrielle, St Genis Laval, France.
François OsiurakLaboratoire d'Étude des Mécanismes Cognitifs (EA 3082), Université de Lyon, Lyon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Humans possess a distinctive capacity for technical reasoning-the ability to infer and manipulate the causal structure of the physical world. Although this faculty is central to technological innovation, its neural substrates remain incompletely understood. Here, we show that grey matter volume in the left area PF, within the supramarginal gyrus of the inferior parietal lobule, may predict individual differences in technical reasoning in healthy adults (N = 75; 54 females; mean age = 20.92 ± 3.28 years). This association remains independent of demographic factors, personality traits, and total brain volume. In contrast, grey matter volume in right prefrontal regions, examined solely as control areas, correlates with broader cognitive functions, such as fluid intelligence and abstract reasoning, but not with technical reasoning. These findings suggest that the left area PF may provide essential computational resources for technical cognition. Located in a parietal area that is disproportionately expanded in humans, the left area PF may serve as a technical hub, functioning as part of a broader fronto-temporo-parietal network that supports the human ability to generate, refine, and pass on complex technologies.

Indexed as

CognitionGray MatterParietal LobeThinkingAdolescentAdultBrain MappingFemaleHumansIntelligenceMagnetic Resonance ImagingMaleYoung AdultCausal reasoningCultureEvolutionNeuroimagingParietal lobeTechnology

Identifiers

PMID41204976

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.