ArticleJournal of applied clinical medical physics2025
Performance evaluation of a second-generation O-ring-shaped image-guided radiotherapy system with a gimbal-mounted linear accelerator and real-time tracking capabilities.
Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Palliative Stereotactic Body Radiotherapy for Metastatic Clear Cell Sarcoma: A Case Report.Cureus · 2026Article
- Initial Experience With Stereotactic Radiosurgery for Refractory Trigeminal Neuralgia Using the OXRAY System.Cureus · 2026Article
- Dynamic tumor tracking for locally advanced pancreatic cancer: precision in motion.Translational cancer research · 2026Article
- Commissioning of an expanded-field radiation technique using a gimbal-mounted linear accelerator.Physics and imaging in radiation oncology · 2026Article
- First clinical implementation of dynamic tumor-tracking volumetric modulated arc therapy with a gimbal-mounted linac: short delivery time and high precision.Journal of radiation research · 2026Article
- Performance evaluation of a second-generation O-ring-shaped image-guided radiotherapy system with a gimbal-mounted linear accelerator and real-time tracking capabilities.Journal of applied clinical medical physics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
purposeOXRAY, a state-of-the-art radiation therapy system commercialized by Hitachi High-Tech Ltd. in 2023, integrates unique beam delivery and image-guided radiation therapy (IGRT) technologies as the successor to Vero4DRT. This study evaluated the performance of this second-generation O-ring-shaped linear accelerator.
methodsThe percentage depth dose (PDD) and off-center ratio (OCR) were calculated using the RayStation 2023B treatment planning system with multileaf collimator-shaped square fields. PDDs were evaluated up to a depth of 250 mm and OCRs at depths of 15, 100, and 200 mm, compared with measurements. Patient-specific quality assurance (PSQA) was conducted for 28 volumetric-modulated arc therapy plans and evaluated using gamma pass rates (GPRs) based on a 3%/2 mm criterion. The biaxial rotational dynamic radiation therapy (BROAD-RT) performance was validated with 25 trajectories. A tracking experiment under rotational irradiation was performed to assess the tracking accuracy. Additionally, image-guidance systems (kV X-ray and kV cone-beam computed tomography) were evaluated using anthropomorphic phantoms. The localization accuracy (LA) was determined by comparing the known offsets with the noted differences between the initial and corrected positions.
resultsDifferences between the calculated and measured data were within the tolerance limits defined in European Society for Radiotherapy and Oncology Booklet 7 and American Association of Physicists in Medicine (AAPM) Medical Physics Practice Guideline 5.b. The median PSQA GPRs exceeded 95%, satisfying AAPM Task Group-218 criteria. BROAD-RT demonstrated submillimeter accuracy (within 0.4 mm), even for complex trajectories. The tracking accuracy remained within 1 mm even during rotational delivery. LA was within 0.5 mm for translational shifts and 0.5° for rotational adjustments.
conclusionOXRAY demonstrated clinically acceptable beam quality and high-precision dose delivery outcomes. The tracking accuracy was maintained under rotational irradiation. Automatic image registration enabled accurate, reproducible patient positioning, supporting reliable IGRT implementation. These findings offer practical guidance and technical benchmarks for institutions adopting OXRAY.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.