ArticleBMC pediatrics2025
Correlation between 25-hydroxyvitamin D, N-terminal pro-brain natriuretic peptide, inflammatory factors and myocardial injury in children with mycoplasma pneumoniae pneumonia.
Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Development of a nomogram to predict acute liver injury in children withFrontiers in pediatrics · 2026Article
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2 authors.
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Abstract
objectiveThe purpose of this study was to examine the relationship between myocardial injury in children with Mycoplasma pneumoniae pneumonia (MPP) and changes in serum 25-hydroxyvitamin D (25-(OH)-D), N-terminal pro-brain natriuretic peptide (NT-proBNP), and related inflammatory factors, including tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), interleukin-6 (IL-6), and high-sensitivity C-reactive protein (hs-CRP).
methodsThe study included 300 children with MPP who were hospitalized to Zhangye People's Hospital, affiliated with Hexi College, between January 2023 and December 2023. Children with myocardial injury were assigned to Group A, while those without were assigned to Group B. The two groups' levels of NT-proBNP, 25-(OH)-D, and associated inflammatory markers were measured and compared.
resultsPearson correlation analysis confirmed the association between myocardial damage and alterations in 25-(OH)-D, NT-proBNP, and associated inflammatory markers in children with MPP. Group A children had lower 25-(OH)-D levels than Group B children (p < 0.05), while Group B children had significantly greater levels of NT-proBNP, TNF-α, IL-1β, IL-6, and hs-CRP (p < 0.05). The results of Pearson correlation analysis revealed that the occurrence of myocardial injury in MPP patients could be associated with the levels of 25-(OH)-D, NT-proBNP, TNF-α, IL-1β, IL-6, and hs-CRP.
conclusionIt can be concluded that MPP patients may experience myocardial injury when 25-(OH)-D levels decrease and NT-proBNP and related inflammatory factors increase. Therefore, changes in the levels of these indicators should be taken into account when carrying out clinical treatment.
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