Evidence map›Paper›PMID 41204130›Full record

Trial reportBMC ophthalmology2025

Safety and effectiveness of orthokeratology for treating myopic regression after LASIK.

Chang Zhang, Wenwei Li, Shudong Jing, Ping Zhao, Chenliang He, Fang Yuan

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chang ZhangDepartment of Ophthalmology, Tongde Hospital of Zhejiang Province, No. 234 Gucui Road, Hangzhou, Zhejiang Province, China.
Wenwei LiDepartment of Ophthalmology, Tongde Hospital of Zhejiang Province, No. 234 Gucui Road, Hangzhou, Zhejiang Province, China.
Shudong JingQuzhou Aier Eye Hospital, No. 3-11, Building 3, Central Business Plaza, No. 39 Baiyunzhong Avenue, Kecheng District, Quzhou, Zhejiang Province, China.
Ping ZhaoDepartment of Ophthalmology, Tongde Hospital of Zhejiang Province, No. 234 Gucui Road, Hangzhou, Zhejiang Province, China.
Chenliang HeDepartment of Ophthalmology, Tongde Hospital of Zhejiang Province, No. 234 Gucui Road, Hangzhou, Zhejiang Province, China.
Fang YuanDepartment of Ophthalmology, Tongde Hospital of Zhejiang Province, No. 234 Gucui Road, Hangzhou, Zhejiang Province, China. yuanfang8451@163.com.

Funding

Zhejiang Provincial Administration of Traditional Chinese Medicine 2026ZL0233
6 · The paper itself

Abstract

purposeThis research was focused on evaluating the safety and efficacy of orthokeratology (Ortho-K) lenses in the management of myopic regression for patients who had previously undergone LASIK surgery.

methodsIn this retrospective, randomized study included 14 Chinese patients (26 eyes) who had undergone LASIK surgery more than 10 years prior and subsequently experienced myopic regression. Over a 30-month period of Ortho-K lens wear, changes in the Bowman's roughness index, corneal and corneal flap thickness were evaluated using optical coherence tomography (OCT). The main goal of the research was to evaluate was to assess the impact of Ortho-K lens use on these parameters in individuals who have undergone LASIK surgery in the past surgery and myopic regression.

resultPrior to fitting the Ortho-K lenses, the average thickness of the central cornea was measured to be 481 ± 24 μm, whereas the thickness of the central corneal flap was found to be 181 ± 18 μm. Additionally, the nasal and temporal corneal flap thicknesses were measured as 145 ± 17 μm and 146 ± 21 μm, respectively. Following a period of Ortho-K lens wear, significant flattening was observed in both the central corneal thickness (461 ± 14 μm, p < 0.05) and central corneal flap thickness (162 ± 26 μm, p < 0.05). Conversely, the nasal and temporal corneal flap thicknesses increased significantly to 164 ± 27 μm (p < 0.05) and 169 ± 23 μm (p < 0.05), respectively. The pre-fitted Bowman's roughness index (BRI) was recorded as 2.367 × 10

conclusionThis work demonstrated the ability to treat myopic progression after LASIK safely and effectively with overnight ortho-K.

Indexed as

Contact LensesKeratomileusis, Laser In SituMyopiaOrthokeratologic ProceduresRefraction, OcularAdultCorneaFemaleFollow-Up StudiesHumansMaleRetrospective StudiesSurgical FlapsTomography, Optical CoherenceTreatment OutcomeVisual AcuityBRICorneal flapLASIKOrthokeratologyRefraction regression

Identifiers

PMID41204130
PMCPMC12598825

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.