Evidence map›Paper›PMID 41204111›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025

Endovascular treatment of unruptured intracranial aneurysms at a single center: Outcomes, selection strategy, and transparent communication for patient decision-making.

Gianmarco Bernava, Abiram Sandralegar, Jeremy Hofmeister, Andrea Rosi, Hasan Yilmaz, Sandrine Morel, Philippe Reymond, Olivier Brina, Michel Muster, Karl-Olof Lovblad and 3 more

Registry-linked trialAbstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05526352 (@neurIST), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05526352 recruitingnot on this map

@neurIST : Informatique biomédicale intégrée Pour la Gestion Des anévrismes cérébraux

Typeobservational_patient_registrySponsorUniversity Hospital, GenevaRan2015 to 2040Enrolled20,000ConditionsIntracranial Aneurysm
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gianmarco BernavaDivision of Neuroradiology, Geneva University Hospitals, Geneva, Switzerland.ORCID 0000-0003-2037-5558
Abiram SandralegarDivision of Neurosurgery, Geneva University Hospitals, Geneva, Switzerland.ORCID 0009-0007-2724-6632
Jeremy HofmeisterDivision of Neuroradiology, Geneva University Hospitals, Geneva, Switzerland.ORCID 0000-0002-0071-8499
Andrea RosiDivision of Neuroradiology, Geneva University Hospitals, Geneva, Switzerland.
Hasan YilmazDivision of Neuroradiology, Geneva University Hospitals, Geneva, Switzerland.
Sandrine MorelDivision of Neurosurgery, Geneva University Hospitals, Geneva, Switzerland.
Philippe ReymondDivision of Neuroradiology, Geneva University Hospitals, Geneva, Switzerland.ORCID 0000-0002-0772-6862
Olivier BrinaDivision of Neuroradiology, Geneva University Hospitals, Geneva, Switzerland.
Michel MusterDivision of Neuroradiology, Geneva University Hospitals, Geneva, Switzerland.
Karl-Olof LovbladDivision of Neuroradiology, Geneva University Hospitals, Geneva, Switzerland.
Karl SchallerDivision of Neurosurgery, Geneva University Hospitals, Geneva, Switzerland.
Philippe BijlengaDivision of Neurosurgery, Geneva University Hospitals, Geneva, Switzerland.
Paolo MachiDivision of Neuroradiology, Geneva University Hospitals, Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundThe management of unruptured intracranial aneurysms (UIA) requires a balance between procedural risks and the potential benefit of rupture prevention.ObjectiveThe aim of this study is to evaluate the clinical and anatomical results of endovascular treatment for UIAs at our institution, to benchmark our practice and potential areas for improvement, and enable transparent communication with patients by providing accurate, evidence-based information.MethodsWe reviewed all patients treated for an UIA between January 2017 and July 2022. Patients were grouped according to treatment technique: simple or balloon-assisted coiling; stent-assisted coiling; or flow-diverter stent placement. Clinical outcomes included perioperative mortality, transient (<3 months), and permanent morbidity (>3 months). Anatomical results were graded with the Raymond-Roy or the O'Kelly-Marotta scales. Retreatment rates, length of hospitalization, readmissions, irradiation time, and total radiation dose were assessed.ResultsIn total, 169 patients with 201 UIAs underwent 187 endovascular procedures without death, 1% permanent morbidity, 8% transient morbidity, and 4% retreatment. The treatment subgroups analysis shows an absence of permanent morbidity associated with flow-diverter stenting and stent-assisted coiling. Simple/balloon-assisted coiling suffered 2.6% permanent morbidity. Transient morbidity was observed in 9%, 9.5%, and 6.6% of flow-diverter stenting, stent-assisted coiling, and simple/balloon-assisted coiling, respectively.ConclusionsIn our hospital, about one in a hundred procedures caused lasting problems, while about one in 25 aneurysms needed a second treatment. These results reflect our case selection and multidisciplinary approach. Reporting them transparently helps patients understand what outcomes to expect at our hospital.

Indexed as

Endovascular treatmentoutcomespatient informed decision-makingunruptured intracranial aneurysm

Identifiers

PMID41204111
PMCPMC12602267

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.