Evidence map›Paper›PMID 41204092›Full record

ArticleBMC primary care2025

Patient-reported characteristics of pernicious anaemia: a first step to initiate James Lind Alliance Priority Setting Partnership driven research.

Alfie Thain, Petra Visser, Kathryn Hart, Ebba Nexo, Andrew McCaddon, Luciana Hannibal, Bruce Hr Wolffenbuttel, Ralph Green, Nicola Ward, Catherine Heidi Seage and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alfie ThainSchool of Biosciences and Medicine, University of Surrey, Guildford, UK.
Petra VisserThe Pernicious Anaemia Society, Bridgend, UK.
Kathryn HartSchool of Biosciences and Medicine, University of Surrey, Guildford, UK.
Ebba NexoDepartment of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark.
Andrew McCaddonFaculty of Social and Life Sciences, Wrexham Glyndwr University, Wrexham, UK.
Luciana HannibalLaboratory of Clinical Biochemistry and Metabolism, Department of General Paediatrics, University of Freiburg, Freiburg, Germany.
Bruce Hr WolffenbuttelDepartment of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Ralph GreenSchool of Medicine, University of California, Davis, CA, USA.
Nicola WardLeicester School of Pharmacy, De Montfort University, Leicester, UK.
Catherine Heidi SeageSchool of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK.
Katrina BurchellThe Pernicious Anaemia Society, Bridgend, UK.
Kourosh R AhmadiSchool of Biosciences and Medicine, University of Surrey, Guildford, UK. k.ahmadi@surrey.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPernicious anaemia (PA) is characterised by vitamin B

methodsAn online survey was designed using SurveyMonkey (SurveyMonkey Inc., San Mateo, CA, USA). It comprised twenty-one questions collecting data on demographics, mode and timing of PA diagnosis, comorbidities, family history of PA or other autoimmune conditions, and type and regime of management. The survey was sent to 3,482 PAS members (April - September 2022) via the PAS website, newsletter, and email.

resultsA total of 1,191 PAS members completed the survey. Of those individuals with a probable (n = 471) or suspected PA (n = 500) diagnosis defined by higher specificity diagnostics 84% were UK-based and 81% were female, with an age-range of 23-93 years. Diagnosis was predominantly based on low serum B

conclusionThis study's findings further highlight the gaps in current diagnostic and management approaches for PA and pave the way forward for future work in accordance with the JLA-PSP research priorities. By characterising a cohort of PA patients and compiling essential baseline data, we provide a foundation for research that supports the development of more effective diagnostic and management strategies.

Indexed as

Anemia, PerniciousAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedSurveys and QuestionnairesYoung AdultAutoimmune diseaseDiagnosisPernicious anaemiaTreatmentVitamin B12 deficiency

Identifiers

PMID41204092
PMCPMC12595726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.