Evidence map›Paper›PMID 41204053›Full record

ArticleNPJ Parkinson's disease2025

Mapping the developmental path for Parkinson's disease therapeutics.

Neel T Dhruv, Sarah Robinson Schwartz, Christine Swanson-Fischer, Hyun Joo Cho, Rebekah Corlew, Lyn Jakeman, Lauren A Laboissonniere, Rebecca Price, Shireen Sarraf, Beth-Anne Sieber and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ Parkinson's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Neel T DhruvNational Institute of Neurological Disorders and Stroke, Bethesda, MD, USA. neel.dhruv@nih.gov.
Sarah Robinson SchwartzNational Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
Christine Swanson-FischerNational Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
Hyun Joo ChoNational Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
Rebekah CorlewNational Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
Lyn JakemanNational Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
Lauren A LaboissonniereNational Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
Rebecca PriceNational Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
Shireen SarrafNational Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
Beth-Anne SieberNational Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
Christine TorborgNational Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
Carl WondersNational Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
Alice Chen-PlotkinDepartment of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
William J MartinJohnson & Johnson, Inc., San Diego, CA, USA.
Amir P TamizNational Institute of Neurological Disorders and Stroke, Bethesda, MD, USA. amir.tamiz@nih.gov.

Funding

Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI A. Clementina Mesaros · 2006 to 2026
$35.3M
Project IV: In Vivo Dissection of Genetic Modifiers on Different Stages of SynucleinopathyP01AG084497 · NIA · UNIVERSITY OF PENNSYLVANIA · PI ALICE S CHEN-PLOTKIN · 2024 to 2026
$15.2M
Understanding biomarkers of cognitive decline in Lewy body diseasesR37NS115139 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI ALICE S CHEN-PLOTKIN · 2024 to 2026
$2.2M
NIA NIH HHS P01 AG084497NIEHS NIH HHS P30 ES013508NINDS NIH HHS R37 NS115139
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41204053
PMCPMC12594996

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.