Evidence map›Paper›PMID 41203903›Full record

ReviewEye (London, England)2026

Management of uveitic and chorioretinal conditions in pregnancy.

Ariel Yuhan Ong, Evita Evangelia Christou, Christine A Kiire, Naomi Primrose, William R Tucker, Charlotte Frise, Samantha R de Silva

Abstract readReview
In one paragraph

Review in Eye (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ariel Yuhan OngOxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.ORCID 0000-0001-9300-573X
Evita Evangelia ChristouOxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.ORCID 0000-0002-7959-4854
Christine A KiireOxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Naomi PrimroseQueen Charlotte's and Chelsea Hospital, Imperial College Healthcare NHS Trust, London, UK.
William R TuckerMoorfields Eye Hospital, Moorfields Eye Hospital NHS Foundation Trust, London, UK.
Charlotte Frise *Queen Charlotte's and Chelsea Hospital, Imperial College Healthcare NHS Trust, London, UK. charlotte.frise@nhs.net.
Samantha R de Silva *Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. samantha.desilva@ndcn.ox.ac.uk.ORCID 0000-0002-4455-2814

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During pregnancy, women may develop de novo sight-threatening chorioretinal diseases or experience exacerbations of these conditions. Examples include macular neovascularisation, diabetic macular oedema, and posterior uveitis. Ophthalmologists may not necessarily recommend the standard treatment for these disorders when they arise in pregnant women due to a lack of evidence regarding safety and potential risks of teratogenicity and fetotoxicity, and a lack of experience with managing this patient population. However, withholding treatment may lead to irreversible maternal vision loss. In this review, we discuss therapies that may need to be considered in these conditions, including steroids, intraocular pressure-lowering treatment for steroid-induced glaucoma, systemic immunosuppressants, and intravitreal anti-vascular endothelial growth factor agents. We discuss the evidence base behind these treatments in terms of safety in pregnancy, bringing in the obstetric perspective. We also discuss common misconceptions surrounding different modes of delivery in pregnant women with chorioretinal disease.

Indexed as

ChorioretinitisPregnancy ComplicationsUveitisAngiogenesis InhibitorsFemaleHumansImmunosuppressive AgentsPregnancyAngiogenesis InhibitorsImmunosuppressive Agents

Identifiers

PMID41203903
PMCPMC12764948

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.