Evidence map›Paper›PMID 41203884›Full record

ArticleCommunications medicine2025

Identifying malaria elimination strategies in the presence of human movement in Bangladesh.

Ayesha S Mahmud, Meng-Chun Chang, Daniel T Citron, Kenth Engø-Monsen, Abdullah Abu Sayeed, Sazid Ibna Zaman, Didar Uddin, Md Mushfiqur Rahman, Mosiqure Rahaman, Md Nazmul Islam and 3 more

Abstract read
In one paragraph

Article in Communications medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ayesha S Mahmud *Department of Demography, University of California Berkeley, Berkeley, CA, USA. mahmuda@berkeley.edu.ORCID http://orcid.org/0000-0002-2282-8613
Meng-Chun Chang *Institute of Bioinformatics and Structural Biology and Department of Life Science, National Tsing Hua University, Hsinchu, Taiwan.
Daniel T CitronDepartment of Population Health, NYU Grossman School of Medicine, New York, NY, USA.
Kenth Engø-MonsenSmart Innovation Norway AS, Halden, Norway.
Abdullah Abu SayeedChittagong Medical College and Hospital, Chattogram, Bangladesh.
Sazid Ibna ZamanMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Didar UddinMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Md Mushfiqur RahmanNational Malaria Elimination Program and ATDs Control Program, Communicable Disease Control, Directorate General of Health Services, Dhaka, Bangladesh.
Mosiqure RahamanNational Malaria Elimination Program and ATDs Control Program, Communicable Disease Control, Directorate General of Health Services, Dhaka, Bangladesh.
Md Nazmul IslamCommunicable Disease Control, Directorate General of Health Services, Dhaka, Bangladesh.
Richard James MaudeMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.ORCID http://orcid.org/0000-0002-5355-0562
Caroline O BuckeeThe Center for Communicable Disease Dynamics and Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID http://orcid.org/0000-0002-8386-5899
Hsiao-Han ChangInstitute of Bioinformatics and Structural Biology and Department of Life Science, National Tsing Hua University, Hsinchu, Taiwan. hhchang@life.nthu.edu.tw.ORCID http://orcid.org/0000-0001-8016-1530

Funding

New approaches to measuring and containing the spatial spread of human pathogensR35GM124715 · NIGMS · HARVARD SCHOOL OF PUBLIC HEALTH · PI BUCKEE, CAROLINE O'FLAHERTY · 2017 to 2021
$2.0M
Novel data and approaches for dynamic modeling of human behavior and infectious disease ecologyR35GM156856 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Ayesha Sanchita Mahmud · 2024 to 2026
$1.2M
Asian Development Bank (ADB) R-CDTA 8485Bill and Melinda Gates Foundation (Bill & Melinda Gates Foundation) OPP1129596Ministry of Science and Technology, Taiwan (Ministry of Science and Technology of Taiwan) NSTC 113-2636-B-007-006NIGMS NIH HHS R35 GM124715NIGMS NIH HHS R35 GM156856U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) R35GM124715-02U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) R35GM156856Wellcome TrustWellcome Trust 220211
6 · The paper itself

Abstract

backgroundMalaria transmission in the Chittagong Hill Tracts (CHT) districts in Bangladesh is characterized by considerable heterogeneity in incidence and the frequent mixing and importation of parasites across districts. Thus, elimination efforts must account for human mobility between endemic and non-endemic locations, and the relative importance of local transmission and parasite importation domestically.

methodsWe construct a metapopulation malaria model, parameterized by human mobility data and fit to epidemiological data, to guide elimination efforts in the region.

resultsWe find substantial heterogeneity in the transmission intensity across the CHT, with the estimated basic reproduction number varying greatly across places with similar levels of observed incidence. When vector control interventions are applied locally, the greatest impact in reducing overall incidence are in places with both high transmission intensity and high connectivity with more populated districts in the western part of the CHT.

conclusionsLocal elimination in several areas with low or intermediate incidence has a moderate impact in reducing overall incidence, indicating that only focusing on high incidence areas is not sufficient for malaria elimination. More generally, our modeling framework can be used to prioritize resource allocation and identify the conditions necessary for malaria elimination in the region.

Identifiers

PMID41203884
PMCPMC12594956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.