Evidence map›Paper›PMID 41203710›Full record

ArticleScientific reports2025

The novel diagnostic value and characteristic imaging features of CT dacryocystography in primary lacrimal canaliculitis.

Lihong Yang, Zhi Yin, Hua Sun, Hongxun Li, Peng Wang, Yuchuan Wang, Lei Zhang, Jiagen Li, Yun Zhao, Ye Pan and 3 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Lihong YangTianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Vision Science, Affiliated Eye Hospital of NanKai University, Clinical College of Ophthalmology of Tianjin Medical University, Tianjin, 300020, China. ylhong922@126.com.
Zhi YinTianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Vision Science, Affiliated Eye Hospital of NanKai University, Clinical College of Ophthalmology of Tianjin Medical University, Tianjin, 300020, China.
Hua SunBeijing Tongren Hospital, Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100005, China.
Hongxun LiTianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Vision Science, Affiliated Eye Hospital of NanKai University, Clinical College of Ophthalmology of Tianjin Medical University, Tianjin, 300020, China.
Peng WangTianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Vision Science, Affiliated Eye Hospital of NanKai University, Clinical College of Ophthalmology of Tianjin Medical University, Tianjin, 300020, China.
Yuchuan WangTianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Vision Science, Affiliated Eye Hospital of NanKai University, Clinical College of Ophthalmology of Tianjin Medical University, Tianjin, 300020, China.
Lei ZhangTianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Vision Science, Affiliated Eye Hospital of NanKai University, Clinical College of Ophthalmology of Tianjin Medical University, Tianjin, 300020, China.
Jiagen LiTianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Vision Science, Affiliated Eye Hospital of NanKai University, Clinical College of Ophthalmology of Tianjin Medical University, Tianjin, 300020, China.
Yun ZhaoTianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Vision Science, Affiliated Eye Hospital of NanKai University, Clinical College of Ophthalmology of Tianjin Medical University, Tianjin, 300020, China.
Ye PanTianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Vision Science, Affiliated Eye Hospital of NanKai University, Clinical College of Ophthalmology of Tianjin Medical University, Tianjin, 300020, China.
Hong ZhaoTianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Vision Science, Affiliated Eye Hospital of NanKai University, Clinical College of Ophthalmology of Tianjin Medical University, Tianjin, 300020, China.
Zhenbiao XuHuanxian People's Hospital, Qingyang City, 745700, Gansu Province, China.
Jing JingHuanxian People's Hospital, Qingyang City, 745700, Gansu Province, China.

Funding

Foudation of Tianjin Eye Hospital YKYB2005Science and Technology Program of Gansu Province 25JRRM010Tianjin Key Medical Discipline Construction TJYXZDXK-3-004A-3
6 · The paper itself

Abstract

To analyze the imaging characteristics and evaluate the diagnostic value of computed tomographic dacryocystography (CT-DCG) in primary canaliculitis. This is a retrospective study from three medical centers. We enrolled 126 primary canaliculitis patients (126 eyes) and 108 non-canaliculitis subjects (134 eyes). All patients with canaliculitis underwent CT-DCG, dacryoendoscopy examination, microbiologic culture, histopathologic staining and canaliculotomy to confirm the definitive diagnosis. Non-canaliculitis cases were diagnosed via dacryoendoscopy and CT-DCG. Demographics, clinical features, and CT-DCG imaging features of primary canaliculitis were evaluated. The diagnostic performance, including sensitivity, specificity, and inter-observer agreement, was also assessed. In the canaliculitis group, the main imaging characteristics of CT-DCG included filling defects, dilation, raggedness, beading, and diverticula formation. Filling defects can serve as a distinctive diagnostic feature of canaliculitis. In our series, CT-DCG showed excellent diagnostic performance with a sensitivity of 94.4%, specificity of 98.5%, and high inter-observer agreement (Cohen’s kappa = 0.85). CT-DCG demonstrates distinct imaging features that enable accurate diagnosis of primary lacrimal canaliculitis. It overcomes limitations of traditional methods, provides comprehensive LDS visualization, and offers valuable preoperative information, establishing it as a superior diagnostic tool.

Indexed as

CanaliculitisDacryocystitisLacrimal ApparatusTomography, X-Ray ComputedAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesSensitivity and SpecificityComputed tomographic dacryocystography (CT-DCG)DacryoendoscopyDiagnostic valueImaging featuresPrimary lacrimal canaliculitis

Identifiers

PMID41203710
PMCPMC12594750

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.