Evidence map›Paper›PMID 41203652›Full record

ArticleScientific reports2025

Cinchona-based liquid formulation exhibits antifungal activity through Tryptophan starvation and disruption of mitochondrial respiration in Rhizoctonia Solani.

Simanta Das, Srinjoy Ghosh, Kumaresh Pal, Moumita Chakraborty, Surajit Khalko, Sk Masudul Islam, Samuel Rai, Ashok Choudhury, Nandita Sahana, Somnath Mandal

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Simanta DasDepartment of Biochemistry, Uttar Banga Krishi Viswavidyalaya, Pundibari, Cooch Behar, 736165, India.
Srinjoy GhoshDepartment of Biochemistry, Uttar Banga Krishi Viswavidyalaya, Pundibari, Cooch Behar, 736165, India.
Kumaresh PalDepartment of Biochemistry, Uttar Banga Krishi Viswavidyalaya, Pundibari, Cooch Behar, 736165, India.
Moumita ChakrabortyDepartment of Genetics and Plant Breeding, Uttar Banga Krishi Viswavidyalaya, Pundibari, Cooch Behar, West Bengal, 736165, India.
Surajit KhalkoDepartment of Plant Pathology, Uttar Banga Krishi Viswavidyalaya, Pundibari, Cooch Behar, West Bengal, 736165, India.
Sk Masudul IslamDirectorate of Cinchona and Other Medicinal Plants, Mungpoo, Darjeeling, West Bengal, 734313, India.
Samuel RaiDirectorate of Cinchona and Other Medicinal Plants, Mungpoo, Darjeeling, West Bengal, 734313, India.
Ashok ChoudhurySoil Microbiology Laboratory, Regional Research Station, Uttar Banga Krishi Viswavidyalaya, Pundibari, Cooch Behar, 736165, India.
Nandita SahanaDepartment of Biochemistry, Uttar Banga Krishi Viswavidyalaya, Pundibari, Cooch Behar, 736165, India. nanditasahana@gmail.com.
Somnath MandalDepartment of Biochemistry, Uttar Banga Krishi Viswavidyalaya, Pundibari, Cooch Behar, 736165, India. smandal8183@gmail.com.

Funding

Department of Food processing Industries and Horticulture, Government of West Bengal, India 485/DCOMP/2022
6 · The paper itself

Abstract

This study investigates the antifungal properties of a liquid Cinchona-Based Formulation (CBF) against Rhizoctonia solani. CBF, a stable acidic extract of Cinchona bark (0.1 N HCl), effectively suppressed mycelial growth (58.75 ± 0.48%) and sclerotia biomass (22.1 ± 0.65 mg), with an EC

Indexed as

Antifungal AgentsMitochondriaPlant ExtractsRhizoctoniaTryptophanFungal ProteinsMembrane Potential, MitochondrialMolecular Docking SimulationReactive Oxygen SpeciesAntifungal AgentsFungal ProteinsPlant ExtractsReactive Oxygen SpeciesTryptophanCinchonaRespirationRhizoctoniaTryptophan starvation

Identifiers

PMID41203652
PMCPMC12594847

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.