Evidence map›Paper›PMID 41203628›Full record

ArticleCell death & disease2025

The transcription factor ZEB2 mediates the antitumor efficacy of tumor-infiltrating lymphocytes in non-small cell lung cancer.

Jiajia Wang, Fei Liu, Yongyong Li, Jiaojiao Gao, Shasha Yang, Mei Tian, Lili Deng, Yan Yang, Beilei Gong, Chengling Zhao and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell death & disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Jiajia Wang *Anhui Province Key Laboratory of Respiratory Tumor and Infectious Disease, the Department of Pulmonary Critical Care Medicine, First Affiliated Hospital of Bengbu Medical University, Bengbu, China.ORCID http://orcid.org/0000-0002-6961-2190
Fei Liu *Anhui Province Key Laboratory of Respiratory Tumor and Infectious Disease, the Department of Pulmonary Critical Care Medicine, First Affiliated Hospital of Bengbu Medical University, Bengbu, China.ORCID http://orcid.org/0000-0003-1746-8454
Yongyong Li *Department of Geriatric Medicine, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Jiaojiao GaoAnhui Province Key Laboratory of Respiratory Tumor and Infectious Disease, the Department of Pulmonary Critical Care Medicine, First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Shasha YangAnhui Province Key Laboratory of Respiratory Tumor and Infectious Disease, the Department of Pulmonary Critical Care Medicine, First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Mei TianAnhui Province Key Laboratory of Respiratory Tumor and Infectious Disease, the Department of Pulmonary Critical Care Medicine, First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Lili DengAnhui Province Key Laboratory of Respiratory Tumor and Infectious Disease, the Department of Pulmonary Critical Care Medicine, First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Yan YangAnhui Province Key Laboratory of Respiratory Tumor and Infectious Disease, Department of Medical Oncology, the First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Beilei GongAnhui Province Key Laboratory of Respiratory Tumor and Infectious Disease, the Department of Pulmonary Critical Care Medicine, First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Chengling ZhaoAnhui Province Key Laboratory of Respiratory Tumor and Infectious Disease, the Department of Pulmonary Critical Care Medicine, First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Huiyuan GongAnhui Province Key Laboratory of Respiratory Tumor and Infectious Disease, Department of Thoracic Surgery, the First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Zongyu XieAnhui Province Key Laboratory of Respiratory Tumor and Infectious Disease, Department of Radiology, the First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Yongchun ZhouAnhui Province Key Laboratory of Respiratory Tumor and Infectious Disease, Department of Radiation Oncology, the First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Rongzhong HuangPrecision Medicine Center, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Qiang LuoKey Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China. qiangluo@hospital.cqmu.edu.cn.
Depeng JiangDepartment of Respiratory Medicine, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, China. gdp116@hospital.cqmu.edu.cn.ORCID http://orcid.org/0009-0005-8467-4559
Xiaojing WangAnhui Province Key Laboratory of Respiratory Tumor and Infectious Disease, the Department of Pulmonary Critical Care Medicine, First Affiliated Hospital of Bengbu Medical University, Bengbu, China. xjwang1975@bbmu.edu.cn.

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82373329
6 · The paper itself

Abstract

Immune checkpoint blockade (ICB) offers an in vivo approach to activate CD8

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsLymphocytes, Tumor-InfiltratingZinc Finger E-box Binding Homeobox 2AnimalsCD8-Positive T-LymphocytesCell Line, TumorFemaleHumansImmune Checkpoint InhibitorsMiceT-bet Transcription FactorT-Box Domain ProteinsImmune Checkpoint InhibitorsT-bet Transcription FactorT-Box Domain ProteinsZEB2 protein, humanZinc Finger E-box Binding Homeobox 2

Identifiers

PMID41203628
PMCPMC12594841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.