Electrochemical deutero-(di)carboxylations for the preparation of deuterium-labeled medicinal building blocks.

Subhojit Mondal, Sahil, Alex Brown, Michael W Meanwell

Abstract read

In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Subhojit MondalDepartment of Chemistry, University of Alberta, 11227 Saskatchewan Dr. NW, Edmonton, T6G 2G2, AB, Canada.ORCID http://orcid.org/0009-0009-8286-2467

SahilDepartment of Chemistry, University of Alberta, 11227 Saskatchewan Dr. NW, Edmonton, T6G 2G2, AB, Canada.ORCID http://orcid.org/0009-0008-1108-1930

Alex BrownDepartment of Chemistry, University of Alberta, 11227 Saskatchewan Dr. NW, Edmonton, T6G 2G2, AB, Canada.ORCID http://orcid.org/0000-0002-5384-9222

Michael W MeanwellDepartment of Chemistry, University of Alberta, 11227 Saskatchewan Dr. NW, Edmonton, T6G 2G2, AB, Canada. meanwell@ualberta.ca.ORCID http://orcid.org/0000-0002-4217-8478

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sacrificial anodes have been broadly deployed in electro-synthesis for the development of reductive electrosynthetic reactions. The metal cations released from sacrificial anodes during these processes are widely believed to not affect reaction outcomes. Here, we disclose an electrochemical deutero-(di)carboxylation of acetylenes and cinnamic acids that in fact relies on anodically generated Mg

Identifiers

PMID41203609

DOI10.1038/s41467-025-64818-9

PMCPMC12594954

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.