Evidence map›Paper›PMID 41203465›Full record

ReviewPaediatric respiratory reviews2026

Respiratory oscillometry in infants: present challenges and future opportunities.

Peter P Moschovis, Danai Christina Theiopoulou, Colm P Travers, Julian Allen, Namasivayam Ambalavanan, Faustine Ceasor, Sotirios Fouzas, Andre G Gie, Samuel Goldfarb, Diane Gray and 21 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Paediatric respiratory reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Peter P MoschovisDivisions of Pediatric Pulmonary Medicine and Global Health, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address: pmoschovis@mgh.harvard.edu.
Danai Christina TheiopoulouDepartment of Pediatrics, Massachusetts General Hospital, Harvard Medical School, Boston, USA. Electronic address: dtheiopoulou@mgh.harvard.edu.
Colm P TraversDivision of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, USA. Electronic address: cptravers@uabmc.edu.
Julian AllenDepartment of Pulmonary and Sleep Medicine, The Children's Hospital of Philadelphia, Philadelphia, USA. Electronic address: ALLENJ@chop.edu.
Namasivayam AmbalavananDivision of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, USA. Electronic address: nambalav@uabmc.edu.
Faustine CeasorDepartment of Pediatrics, Massachusetts General Hospital, Harvard Medical School, Boston, USA. Electronic address: fceasor@mgh.harvard.edu.
Sotirios FouzasPaediatric Respiratory Unit, Department of Paediatrics, University Hospital of Patras, Patras, Greece. Electronic address: sfouzas@upatras.gr.
Andre G GieDepartment of Paediatrics and Child Health, Faculty of Medicine, Stellenbosch University, Stellenbosch, South Africa. Electronic address: agie@sun.ac.za.
Samuel GoldfarbDivision of Pediatric Pulmonary and Sleep Medicine, Department of Pediatrics, University of Minnesota, Minneapolis, USA. Electronic address: goldf091@umn.edu.
Diane GrayDepartment of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa. Electronic address: diane.gray@uct.ac.za.
Zoltán HantosSemmelweis University, Budapest, Hungary. Electronic address: hantos.zoltan@med.u-szeged.hu.
Narayan Prabhu IyerChildren's Hospital of Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, USA. Electronic address: niyer@chla.usc.edu.
Larry C LandsMontreal Children's Hospital, McGill University, Montreal, Canada. Electronic address: larry.lands@McGill.Ca.
Anna LavizzariNeonatal Intensive Care Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy. Electronic address: anna.lavizzari@policlinico.mi.it.
Winston M ManimtimChildren's Mercy Kansas City, University of Missouri Kansas City, Kansas City, USA. Electronic address: wmmanimtim@cmh.edu.
Eric D McCollumGlobal Program of Pediatric Respiratory Sciences, Johns Hopkins School of Medicine, Baltimore, USA. Electronic address: emccoll3@jhmi.edu.
Andrew MutekangaMbarara University of Science & Technology, Mbarara, Uganda. Electronic address: mutekanga.andrew7@gmail.com.
Clement L RenChildren's Hospital of Philadelphia, Philadelphia, PA, USA. Electronic address: renc@chop.edu.
Natalia RestrepoThorasys Thoracic Medical Systems Inc., Montreal, Canada. Electronic address: nrestrepohoyos@gmail.com.
Paul D RobinsonChildren's Health and Environment Program, Child Health Research Centre, The University of Queensland, Brisbane, Australia. Electronic address: paul.robinson@uq.edu.au.
Shannon J SimpsonWal-Yan Respiratory Research Centre, The Kids Research Institute, Australia. Electronic address: Shannon.Simpson@thekids.org.au.
Peter D SlyChildren's Health and Environment Program, Child Health Research Centre, The University of Queensland, Brisbane, Australia. Electronic address: p.sly@uq.edu.au.
Robert S TepperDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, USA. Electronic address: rtepper@iu.edu.
Alexander ThomopulosEmory University, Atlanta, USA. Electronic address: athomop@emory.edu.
Marieke M van der ZalmDepartment of Paediatrics and Child Health, Faculty of Medicine, Stellenbosch University, Stellenbosch, South Africa. Electronic address: mariekevdzalm@sun.ac.za.
Chiara VeneroniDEIB, Politecnico di Milano, Italy. Electronic address: chiara.veneroni@polimi.it.
Charl VerweyDivision of Paediatric Pulmonology, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa. Electronic address: Charl.Verwey@wits.ac.za.
Emanuela ZanninIRCCS San Gerardo dei Tintori, Monza, Italy. Electronic address: emanuela.zannin@gmail.com.
Heather J ZarDepartment of Paediatrics & Child Health and SA-MRC Unit on Child & Adolescent Health, University of Cape Town, South Africa. Electronic address: heather.zar@uct.ac.za.
Serge M ZigabeCentre for Tropical Diseases and Global Health, Department of Pediatrics, Université Catholique de Bukavu, Bukavu, Democratic Republic of the Congo. Electronic address: serge.zigabe@kuleuven.be.
Lennart K A LundbladMeakins-Christie Labs, McGill University, Montreal, Canada. Electronic address: lennart.lundblad@mcgill.ca.

Funding

Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School AgeR01HL157256 · NHLBI · NORTHWESTERN UNIVERSITY · PI Namasivayam Ambalavanan, NELSON R CLAURE · 2022 to 2026
$7.7M
Let-7b in BPDR01HL156275 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Namasivayam Ambalavanan · 2023 to 2026
$2.2M
The effect of household air pollution on lung function growth in infants with pneumonia in sub-Saharan Africa.K23ES030399 · NIEHS · MASSACHUSETTS GENERAL HOSPITAL · PI MOSCHOVIS, PETER P · 2019 to 2024
$1.1M
Non-invasive oscillometry to measure lung mechanics, response to treatments, and predict longer-term pulmonary outcomes among preterm infants: a prospective cohort studyK23HL157618 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Colm Peter Travers · 2022 to 2026
$862k
The long-term consequences of pulmonary tuberculosis and respiratory viruses on lung health in young South African childrenK43TW011028 · FIC · STELLENBOSCH UNIVERSITY · PI VAN DER ZALM, MARIEKE MARGREET · 2020 to 2024
$647k
Optimizing air purification strategies to reduce household PM2.5 exposure in UgandaR21ES036797 · NIEHS · MASSACHUSETTS GENERAL HOSPITAL · PI MOSCHOVIS, PETER P · 2024 to 2025
$474k
FIC NIH HHS K43 TW011028NHLBI NIH HHS K23 HL157618NHLBI NIH HHS R01 HL156275NHLBI NIH HHS R01 HL157256NIEHS NIH HHS K23 ES030399NIEHS NIH HHS R21 ES036797
6 · The paper itself

Abstract

Despite a high burden of respiratory disease among infants globally, limited options exist for lung function testing in this age group. Tidal breathing techniques such as oscillometry allow for understanding the pathophysiology of diseases that originate early in life, thus providing the opportunity to develop timely prevention and treatment strategies. This review summarises the principles of infant oscillometry, the primary oscillometry measures, physiological differences compared to older age groups, commonly used testing platforms, laboratory benchmarking, and future directions for research. Expanding the use of infant oscillometry will require further standardisation of equipment, calibration, protocols, and technical standards, followed by well-designed studies to outline clinical utility. While infant oscillometry is currently limited to the research setting, this technique has the potential for clinical applications in the future, ultimately providing opportunities for improving respiratory outcomes in infants globally.

Indexed as

OscillometryRespiratory Function TestsHumansInfantInfant, NewbornInfantOscillometryPhysiologyRespiratory function tests

Identifiers

PMID41203465
PMCPMC12765599

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.