Evidence map›Paper›PMID 41203269›Full record

Trial reportJournal of epidemiology and community health2026

Effects of a whole-school relationships and sexual health intervention on non-competent sexual debut: cluster-randomised trial.

Ruth Ponsford, Rebecca Meiksin, Joanna Sturgess, Veena Muraleetharan, Nerissa Tilouche, Charles Opondo, Steve Morris, G J Melendez-Torres, Josephine McAllister, Neisha Sundaram and 8 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of epidemiology and community health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ruth PonsfordDepartment of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, London, UK.
Rebecca MeiksinDepartment of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, London, UK.
Joanna SturgessDepartment of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.
Veena MuraleetharanDepartment of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, London, UK.
Nerissa TiloucheDepartment of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, London, UK.
Charles OpondoDepartment of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.
Steve MorrisDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, Cambridgeshire, UK.
G J Melendez-TorresUniversity of Exeter, Exeter, Devon, UK.
Josephine McAllisterDepartment of Social and Policy Sciences, University of Bath, Claverton Down, Bath, UK.
Neisha SundaramDepartment of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, London, UK.
Alison HadleyUniversity of Bedfordshire, Luton, England, UK.
Maria LohanQueen's University Belfast EPS, Belfast, Northern Ireland, UK.
Catherine Heather MercerInfection and Population Health, University College London, London, UK.
Honor YoungSchool of Social Sciences, Cardiff University, cardiff, UK.
Rona CampbellUniversity of Bristol, Bristol, England, UK.
Karin CoyleETR Associates, Scotts Valley, California, USA.
Elizabeth AllenDepartment of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, London, UK.
Chris BonellDepartment of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, London, UK chris.bonell@lshtm.ac.uk.ORCID http://orcid.org/0000-0002-6253-6498

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRelationships and sex education (RSE) impacts some sexual behaviours but could be strengthened by incorporating whole-school approaches (eg, building engagement, providing contraception). These can prevent pregnancies and sexually-transmitted infections but are unevaluated in UK schools.

methodsA cluster-randomised trial of 'Positive Choices' compared it with usual practice in English secondary schools. Intervention comprised: RSE, school-health-promotion councils involving students, student-needs data to tailor provision; student-led campaigns; review of sexual-health services; and parent information. The primary outcome was prevention of non-competent sexual debut (lacking decision autonomy, judging timing as right, partners' equal willingness or contraception).

resultsOf 2845 schools invited, 50 (1.76%) consented, 1 leaving post-allocation. Of 25 control and 24 intervention schools, 4 withdrew pre-endline. 6970 (77.3%) students participated at baseline and 6268 (77.9%) at 33-month endline. Fidelity of whole-school components was suboptimal. No schools achieved 'good' fidelity; two achieved 'adequate' fidelity across components. 11 achieved 'adequate fidelity on selected components' (student-needs report, school-health-promotion council meetings, lessons, parent information). Control schools delivered similar activities to intervention schools. Among 780 (12.44%) students sexually debuting between baseline and endline, non-competent debut was reported by 268 (64.42%) in the control and 240 (65.93%) in the intervention group (risk difference=0.020 (95% CI -0.05 to 0.09)). There were no effects on secondary outcomes. Incremental costs were £1337 per school (£10 per student).

conclusionPositive Choices did not prevent non-competent sexual debut (primary outcome) or impact secondary outcomes compared with usual RSE, possibly explained by weak fidelity of whole-school elements and/or comprehensive RSE in control schools. TRIAL REGISTRATION NUMBER: ISRCTN16723909.

Indexed as

Health PromotionSchool Health ServicesSex EducationSexual BehaviorSexual HealthStudentsAdolescentFemaleHumansMaleSchoolsSexually Transmitted DiseasesUnited KingdomADOLESCENTRANDOMIZED CONTROLLED TRIALSEX EDUCATIONSEXUAL HEALTH

Identifiers

PMID41203269
PMCPMC13018737

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.