Evidence map›Paper›PMID 41202390›Full record

ArticleBreast (Edinburgh, Scotland)2025

Evaluation of breast cancer screening programmes: Candidate performance indicators and their association with breast cancer mortality.

Carlos Canelo-Aybar, Pablo Alonso-Coello, Sergei Muratov, Jean-Eric Tarride, Nadya Dimitrova, Francesco Giusti, Bettina Borisch, Xavier Castells, Stephen W Duffy, Patricia Fitzpatrick and 11 more

Abstract read
In one paragraph

Article in Breast (Edinburgh, Scotland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Carlos Canelo-AybarIberoamerican Cochrane Center, Barcelona, Spain; Institut de Recerca Sant Pau (IR Sant Pau), Barcelona, Spain.
Pablo Alonso-CoelloInstitut de Recerca Sant Pau (IR Sant Pau), Barcelona, Spain; CIBER Biomedical Research Center in Epidemiology and Public Health (CIBERESP), Health Institute Carlos III (ISCIII), Madrid, Spain. Electronic address: palonso@santpau.cat.
Sergei MuratovDepartment of Health Research Methods, Evidence, and Impact, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
Jean-Eric TarrideDepartment of Health Research Methods, Evidence, and Impact, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
Nadya DimitrovaEuropean Commission, Joint Research Centre, Via E. Fermi 2749 - TP 127, I-21027, Ispra, VA, Italy; Public Health Officer, International Agency for Research on Cancer, Lyon, France.
Francesco GiustiEuropean Commission, Joint Research Centre, Via E. Fermi 2749 - TP 127, I-21027, Ispra, VA, Italy.
Bettina BorischInstitute of Global Health, University of Geneva, Geneva, Switzerland.
Xavier CastellsIMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.
Stephen W DuffyCentre for Prevention, Detection and Diagnosis, Wolfson Institute of Population Health, Queen Mary University of London, London, UK.
Patricia FitzpatrickNational Screening Service, Dublin, Ireland; UCD School of Public Health, Physiotherapy & Sports Science, Dublin, Ireland.
Markus FollmannGerman Cancer Society, Berlin, Germany.
Livia GiordanoCPO-Piedmont - AOU Città della Salute e della Scienza, Torino, Italy.
Solveig HofvindCancer Registry of Norway, Oslo, Norway.
Annette LebeauUniversity Medical Center Hamburg-Eppendorf, Hamburg, Germany; Private Group Practice for Pathology, Lübeck, Germany.
Cecily QuinnSt. Vincent's University Hospital, Dublin, Ireland; University College Dublin, Ireland.
Alberto TorresinDepartment of Physics, Università Statale di Milano (UNIMI), Milan, Italy.
Paolo Giorgi RossiAUSL Reggio Emilia, IRCCS, Reggio Emilia, Italy.
Holger SchünemannDepartment of Health Research Methods, Evidence, and Impact, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
Lennarth NyströmDepartment of Epidemiology and Global Health, Umeå University, Umeå, Sweden.
Mireille BroedersIQ Health Science department, Radboud University Medical Center, Nijmegen, the Netherlands; Dutch Expert Centre for Screening, Nijmegen, the Netherlands. Electronic address: mireille.broeders@radboudumc.nl.
ECIBC contributor group

Funding

World Health Organization 001
6 · The paper itself

Abstract

aimEvaluation of a breast cancer (BC) screening programme is necessary to ensure its quality. Performance measurements might be prioritized considering the association with outcomes related to BC mortality. We piloted an approach to explore the association of selected performance measurements with incidence-based BC mortality (IBM).

methodsWe performed an ecological analysis of aggregated data from regional or national population-based cancer registries and BC screening programmes in Europe, using 13 performance indicators. We built a panel data (longitudinal cross-sectional) regression model to estimate the association between screening performance measurements and IBM rates.

resultsWe included data of 9 programmes and registries from Italy, Spain, Norway, Ireland and the Czech Republic. The number of screening years included in the dataset ranged from 5 to 20 years. In adjusted panel analyses, higher screening coverage, breast cancer detection rates (BCDR prevalent and subsequent rounds), node-negative proportion, and episode sensitivity were associated with lower incidence-based mortality (IBM), whereas a higher interval cancer rate was associated with higher IBM. The association for recall rate in subsequent examinations was small and imprecise.

conclusionOur pilot approach suggests association of several performance indicators with IBM. These indicators were related to the implementation of the screening programme (screening coverage), sensitivity (BC detection rate), and efficiency (recall rate). Further studies with larger datasets and individual data may confirm these findings.

Indexed as

Breast NeoplasmsEarly Detection of CancerMass ScreeningProgram EvaluationQuality Indicators, Health CareAgedCross-Sectional StudiesEuropeFemaleHumansIncidenceMiddle AgedPilot ProjectsRegistriesBreast Neoplasms/diagnostic imaging∗Early detection of Cancer∗/methodsFemaleMass screening/methodsProgram evaluationQuality indicators, health care/standards∗

Identifiers

PMID41202390
PMCPMC12683141

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.