Evidence map›Paper›PMID 41202292›Full record

ArticleJMIR mental health2025

Digital Conversational Agents for the Mental Health of Treatment-Seeking Youth: Scoping Review.

Lisa D Hawke, Jingyi Hou, Anh T P Nguyen, Thalia Phi, Jamie Gibson, Brian Ritchie, Gillian Strudwick, Terri Rodak, Louise Gallagher

Abstract readScoping Review
In one paragraph

Article in JMIR mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lisa D HawkeCentre for Addiction and Mental Health, Toronto, Canada.ORCID 0000-0003-1108-9453
Jingyi HouCentre for Addiction and Mental Health, Toronto, Canada.ORCID 0000-0001-9028-6898
Anh T P NguyenCentre for Addiction and Mental Health, Toronto, Canada.ORCID 0000-0002-8053-4875
Thalia PhiCentre for Addiction and Mental Health, Toronto, Canada.ORCID 0009-0006-3791-406X
Jamie GibsonCentre for Addiction and Mental Health, Toronto, Canada.ORCID 0009-0004-5165-3869
Brian RitchieKama.AI, Toronto, ON, Canada.ORCID 0009-0000-7147-9934
Gillian StrudwickCentre for Addiction and Mental Health, Toronto, Canada.ORCID 0000-0002-1080-7372
Terri RodakCentre for Addiction and Mental Health, Toronto, Canada.ORCID 0000-0002-0584-1429
Louise GallagherCentre for Addiction and Mental Health, Toronto, Canada.ORCID 0000-0001-9462-2836

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDigital conversational agents (or "chatbots") that can generate human-like conversations have recently been adapted as a means of administering mental health interventions. However, their development for youth seeking mental health services requires further investigation.

objectiveThis youth-engaged scoping review synthesizes the recent research on digital conversational agents for youth seeking mental health or substance use services.

methodsStudies were included if they were published between 2016 and 2025 and examined digital conversational agents for youth aged 11 to 24 years with mental health or substance use challenges in clinical settings. Systematic literature searches were conducted in February 2024 in multiple databases and updated in March 2025. Data were extracted using codeveloped forms and synthesized narratively.

resultsTen studies were included, all focusing on mental health. Seven examined the acceptability and feasibility of digital conversational agents; others explored youth perceptions of use, design, and content, with some exploration of impact on mental health symptoms. Eight of ten studies reported high acceptability or positive user experiences. Three were randomized controlled trials that found potential reductions in depressive symptoms. Reporting on the ethical standards was limited. No studies focused on substance use alone.

conclusionsLiterature on digital conversational agents for treatment-seeking youth is emerging but limited. Future rigorous research is needed that prioritizes data security, safety measures, and youth co-design in the development of safe, engaging, digital conversational agents for youth with mental health conditions.

Indexed as

CommunicationMental DisordersMental Health ServicesAdolescentChildHumansMental HealthSubstance-Related DisordersYoung Adultartificial intelligencechatbotmental healthsubstance useyouth

Identifiers

PMID41202292
PMCPMC12639337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.