SynthesisThe international journal of cardiovascular imaging2026
Anomalous left coronary artery from the pulmonary artery in adults: a systematic review of clinical presentation, diagnosis, and outcomes.
Synthesis in The international journal of cardiovascular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Coronary Arterial Anomalies in Adults with Congenital Heart Disease: From Detection to Management Strategies.Journal of cardiovascular development and disease · 2026Review
- Four-dimensional flow CMR-based hemodynamic assessment of ALCAPA: A case report.Radiology case reports · 2026Article
- Coronary Artery Anomalies and Anatomical Variants: Cross-Sectional Diagnostic Imaging and Clinical Background.Journal of imaging · 2026Review
- Anomalous Left Coronary Artery from the Pulmonary Artery: Cinematic Volume Rendering Technique for Enhanced Anatomic Visualization.Diagnostics (Basel, Switzerland) · 2026Article
- The role of multimodality imaging in diagnosing an adult-type anomalous origin of the left coronary artery from the pulmonary artery: A case report.The Journal of international medical research · 2026Article
- Case Report: Atrial fibrillation as the initial presentation of an adult anomalous origin of the left coronary artery from the pulmonary artery.Frontiers in cardiovascular medicine · 2026Article
- Assessment of Coronary Arteries during the Prenatal and Postnatal Periods using Two- and Three-dimensional Ultrasound.Journal of cardiovascular echographyArticle
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Abnormal left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital coronary anomaly, occurring in approximately 1 in 300 000 live births and accounting for roughly 0,5 per cent of all congenital heart defects. Without surgical correction, in more than 90% of cases, the defect leads to death in the first year of life. However, a small subgroup of individuals survive into adulthood. In adults, it can manifest as dyspnoea, angina, palpitations and eventually leads to heart failure, arrhythmia and sudden cardiac death. We summarised 60 years of case reports of ALCAPA syndrome in adults and identified 279 patients, the majority of whom were women. In most cases, the diagnosis was based on coronary angiography. The most common symptom was dyspnoea and the least frequent were palpitations. Surgery was performed in 194 patients with a mean age at surgery of 37,46 years. The aim of this study is to obtain clinically relevant information that would be unattainable even in large multicentre clinical trials, given the rarity of this anomaly. This is the first review juxtaposing all ALCAPA cases in adults published in 60 years.
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