Evidence map›Paper›PMID 41201691›Full record

ArticleMycopathologia2025

Assessing the Validity and Impact of Remote Digital Image Reading in Fungal Diagnostics.

Vilhelmina Lundgren, Özlem Dogan, Anna Ekwall-Larson, Christine Stenström, Erja Chryssanthou, Maria Guglielmeti, Ylva Närström, Patrik Dinnétz, Silvia Botero-Kleiven, Volkan Özenci

Erratum issuedAbstract read
In one paragraph

Article in Mycopathologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Vilhelmina LundgrenDivision of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden.
Özlem DoganDivision of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden.
Anna Ekwall-LarsonDivision of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden.
Christine StenströmDepartment of Clinical Microbiology, Karolinska University Hospital, Solna, Sweden.
Erja ChryssanthouDepartment of Clinical Microbiology, Karolinska University Hospital, Solna, Sweden.
Maria GuglielmetiDepartment of Clinical Microbiology, Karolinska University Hospital, SE 141 86, Huddinge, Stockholm, Sweden.
Ylva NärströmDepartment of Clinical Microbiology, Karolinska University Hospital, SE 141 86, Huddinge, Stockholm, Sweden.
Patrik DinnétzSchool of Natural Sciences, Technology and Environmental Studies, Södertörn University, Huddinge, Sweden.
Silvia Botero-KleivenDivision of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden.
Volkan ÖzenciDivision of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden. volkan.ozenci@ki.se.ORCID http://orcid.org/0000-0002-8069-4027

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycological diagnostics play a crucial role in patient management and treatment of invasive fungal infections. Despite the significant global burden of fungal diseases, awareness and diagnostic capabilities in mycology laboratories lag behind other microbiological disciplines. Mycological diagnostics often require microscopic analysis of clinical samples and culture. The interpretation of microscopy requires extensive expertise in clinical mycology. This study aimed to explore the feasibility of remote digital reading for preliminary identification of fungi. In this study, five mycology-trained participants were asked to analyze a total of 474 images divided into three main groups of yeasts (73 images), filamentous fungi (341 images), and direct fluorescent microscopy from clinical samples (60 images). The accuracy of the assessments varied, with an average correct decision rate between 78 and 93% across the three image groups. Individual participant's performance showed a mean accuracy rate ranging between 76 and 92%. A significant difference was observed in the assessment accuracy across specimen groups and among individual participants (p < 0.05). However, there was no significant interaction effect between participants and image group (p = 0.118). In conclusion, telemycology offers a promising alternative to standard microscopy diagnostics of fungal infections, especially in settings where skilled mycologists are lacking, including low- and middle-income countries.

Indexed as

FungiImage Processing, Computer-AssistedMicroscopyMycologyMycosesHumansReproducibility of ResultsClinical mycologyDigital diagnosticsInvasive fungal infectionsTelemycology

Identifiers

PMID41201691
PMCPMC12594703

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.